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经验公式(希尔记法):
C14H4N2O2S2
化学文摘社编号:
分子量:
296.32
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
222-098-6
Beilstein/REAXYS Number:
1325563
MDL number:
InChI key
PYZSVQVRHDXQSL-UHFFFAOYSA-N
InChI
1S/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H
SMILES string
O=C1C2=C(SC(C#N)=C(S2)C#N)C(=O)c3ccccc13
grade
analytical standard
product line
PESTANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
agriculture
environmental
format
neat
Quality Level
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General description
Dithianons belong to the quinone class of fungicides.
Application
Dithianon may be used as an analytical reference standard for the determination of dithianon in:
- Surface water samples by solid-phase extraction (SPE) and liquid chromatography coupled to quadrupole time-of-flight mass spectrometry (LC-Q-TOFMS).
- Honeybees by dispersive-SPE followed by liquid and gas chromatography coupled to tandem mass spectrometry (LC-MS/MS and GC-MS/MS) equipped with electrospray ionization (ESI) and multiple reaction monitoring (MRM) detection.
- Apples by quick, easy, cheap, effective, rugged and safe (QuEChERS) extraction as well as high performance thin-layer chromatography (HPTLC) clean-up procedures and GC-MS/MS.
- Tomatoes by QuEChERS extraction and LC coupled to triple quadrupole (QqQ) ESI-MS/MS with MRM detection.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
农药列管产品
此项目有
P Perocco et al.
Environmental and molecular mutagenesis, 21(1), 81-86 (1993-01-01)
Cytotoxic and cell transforming activities of the pesticides cyanazine, diflubenzuron, dithianon, procymidone, and vinclozolin were investigated in vitro by utilizing the BALB/c 3T3 cell transformation test performed in the presence or in the absence of S-9 mix as an exogenous
Mikhail Y Syromyatnikov et al.
Pesticide biochemistry and physiology, 169, 104675-104675 (2020-08-24)
Bumblebees are important for crop pollination. Currently, the number of pollinators is decreasing worldwide, which is attributed mostly to the widespread use of pesticides. The aim of this work was to develop a method for assessing the genotoxicity of pesticides
M Paolini et al.
Cancer letters, 113(1-2), 221-228 (1997-02-26)
The ability of dithianon, whose mutagenic/cocarcinogenic activity has as yet not been clarified, to affect specific biomarkers of effect related to non-genotoxic cocarcinogenesis was investigated. For this purpose, several CYP-dependent reactions have been studied in liver, kidney and lung microsomes
Automated online solid-phase extraction-liquid chromatography mass spectrometric analysis of dithianon in water.
Passoni A, et al.
Eur. J. Mass Spectrom., 22(5), 261-267 (2016)
E Sturdík et al.
Chemico-biological interactions, 30(1), 105-104 (1980-04-01)
The inhibition of glycolysis by 2,3-dinitrilo-1,4-dithia-9,10-antraquinone (DDA) in Ehrlich ascites carcinoma (EAC) cells as well as in the investigated respiratory and fermentative strains of yeasts was found to be the result of inactivation of thiol enzymes of this pathway. Increasing
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