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Merck
CN

447293

Sigma-Aldrich

5(6)-羧基荧光素

Dye content 90 %

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About This Item

经验公式(希尔记法):
C21H12O7
CAS号:
分子量:
376.32
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47

检测方案

≥89.5% (HPLC)

质量水平

形式

powder

组成

Dye content, 90%

mp

275 °C (dec.) (lit.)

λmax

492 nm

ε (消光系数)

12134 at 284 nm in 0.1 M NaOH at 0.005 g/L
43060 at 239 nm in 0.1 M NaOH at 0.005 g/L

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

OC(=O)c1ccc2c(c1)C(=O)OC23c4ccc(O)cc4Oc5cc(O)ccc35.OC(=O)c6ccc7C(=O)OC8(c9ccc(O)cc9Oc%10cc(O)ccc8%10)c7c6

InChI

1S/2C21H12O7/c22-11-2-5-15-17(8-11)27-18-9-12(23)3-6-16(18)21(15)14-4-1-10(19(24)25)7-13(14)20(26)28-21;22-11-2-5-14-17(8-11)27-18-9-12(23)3-6-15(18)21(14)16-7-10(19(24)25)1-4-13(16)20(26)28-21/h2*1-9,22-23H,(H,24,25)

InChI key

BPVHBBXCESDRKW-UHFFFAOYSA-N

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WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Suguru Nakagawa et al.
Investigative ophthalmology & visual science, 53(9), 5154-5160 (2012-06-15)
To investigate the toxicity profiles of seven antiglaucoma topical eye drops and benzalkonium chloride (BAC) using stratified cultivated human corneal epithelial cell sheets (HCES) in a serum-free culture system. A range of prostaglandin analogies and preservatives, including BAC, sofZia (SZ)
Martin Hossann et al.
Journal of controlled release : official journal of the Controlled Release Society, 162(2), 400-406 (2012-07-05)
Thermosensitive liposomes (TSL) are a promising tool for triggered drug delivery in combination with local hyperthermia. Objective of this study was to investigate the influence of serum on TSL in more detail and to identify serum components which are responsible
Wensheng Chen et al.
PloS one, 7(7), e40893-e40893 (2012-07-21)
Preservatives are a major component of the ophthalmic preparations in multi-dose bottles. The purpose of this study was to investigate the acute effect of benzalkonium chloride (BAC), a common preservative used in ophthalmic preparations, on the localization and expression of
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Nonionic polyethylene glycol (PEG) as a stealth polymer destabilizes liposomes due to its amphiphilic property. As a result, PEGylated liposomes have to be further stabilized, such as by using a large amount cholesterol. This is a long existing dilemma faced

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