Application
- 用于啮齿目动物中枢和周围神经系统结构中有髓轴突计数的大型树脂截面（resin section）的制备方法: 该研究展示了一种利用Durcupan ACM制备大型树脂截面的技术，改善了啮齿目动物中枢和周围神经系统中有髓轴突的分析 (Dzurjašková et al., 2021） （Dzurjašková et al., 2021）。
- 用于研究神经组织EM制剂3D模型中细胞腔室的三维沉浸虚拟现实。: 该研究在电子显微镜法中采用 Durcupan ACM来构建神经组织的3D模型，促进了沉浸式虚拟现实研究 （Calì et al., 2016) (Calì et al., 2016）。
- 哌唑嗪和氯沙坦给药对年轻Wistar大鼠和SHR血压、心脏、颈动脉和乙酰胆碱诱导心血管系统扩张的长期作用。.: 以用于详细组织分析的含Durcupan ACM样品探索了大鼠中的心血管作用（Kristek et al., 2013）（Kristek et al., 2013）。
Features and Benefits
Mixtures of Durcupan ACM present an interesting alternative to methacrylates for embedding sections for electron microscopy. They present the advantage that they harden uniformly, practically without shrinkage. All fixing agents normally used for electronmicroscopic work are also suitable for the Durcupan ACM embedding process. This process consists of three phases: dehydration of the tissue with acetone or ethyl alcohol, infiltration with the embedding agent, followed by hardening.
General description
Awater-soluble embedding medium for EM based on an aliphatic polyepoxide.
Legal Information
Durcupan is a trademark of Sigma-Aldrich Chemie GmbH
signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 1B - Skin Corr. 1B - Skin Sens. 1
存储类别
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Nicholas J Strausfeld et al.
The Journal of comparative neurology, 528(2), 261-282 (2019-08-04)
Brain centers possessing a suite of neuroanatomical characters that define mushroom bodies of dicondylic insects have been identified in mantis shrimps, which are basal malacostracan crustaceans. Recent studies of the caridean shrimp Lebbeus groenlandicus further demonstrate the existence of mushroom
Enric Llorens-Bobadilla et al.
Science (New York, N.Y.), 370(6512) (2020-10-03)
Injuries to the central nervous system (CNS) are inefficiently repaired. Resident neural stem cells manifest a limited contribution to cell replacement. We have uncovered a latent potential in neural stem cells to replace large numbers of lost oligodendrocytes in the
Małgorzata Alicja Śliwińska et al.
Cerebral cortex (New York, N.Y. : 1991), 30(4), 2573-2585 (2019-12-05)
It is generally accepted that formation and storage of memory relies on alterations of the structure and function of brain circuits. However, the structural data, which show learning-induced and long-lasting remodeling of synapses, are still very sparse. Here, we reconstruct
Hanne Halkinrud Thoen et al.
The Journal of comparative neurology, 528(7), 1079-1094 (2019-10-18)
Mantis shrimps (Stomatopoda) possess in common with other crustaceans, and with Hexapoda, specific neuroanatomical attributes of the protocerebrum, the most anterior part of the arthropod brain. These attributes include assemblages of interconnected centers called the central body complex and in
Rational Design of Bioavailable Photosensitizers for Manipulation and Imaging of Biological Systems.
Thomas C Binns et al.
Cell chemical biology, 27(8), 1063-1072 (2020-07-23)
Light-mediated chemical reactions are powerful methods for manipulating and interrogating biological systems. Photosensitizers, compounds that generate reactive oxygen species upon excitation with light, can be utilized for numerous biological experiments, but the repertoire of bioavailable photosensitizers is limited. Here, we
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