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434760

Sigma-Aldrich

苯甲脒 盐酸盐

99%

别名:

Amidinobenzene hydrochloride, Benzamidinium chloride

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About This Item

线性分子式:
C6H5C(=NH)NH2 · HCl
CAS号:
1670-14-0
分子量:
156.61
Beilstein:
3594959
EC 号:
216-795-4
MDL编号:
MFCD00013025
UNSPSC代码:
12352106
PubChem化学物质编号:
24867207
NACRES:
NA.77

质量水平

200

方案

99%

表单

beads

mp

169-173 °C (lit.)

溶解性

water: soluble

SMILES字符串

Cl.NC(=N)c1ccccc1

InChI

1S/C7H8N2.ClH/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H3,8,9);1H

InChI key

LZCZIHQBSCVGRD-UHFFFAOYSA-N

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应用

<ul>
<li><strong>有机粉尘中丝氨酸蛋白酶的纯化、鉴定及其对肺部炎症介质的诱导作用</strong></li>
<li><strong>达比加群治疗胰蛋白酶依赖性胰腺炎的临床前试验：</strong>本研究使用盐酸苄脒抑制胰腺炎模型中的丝氨酸蛋白酶，突出了其在临床前研究中评估炎症和消化系统疾病新治疗方法的潜力（Pesei et al., 2022）。</li>
</ul>

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000358947
0000358947
0000256897
WXBF0199V
MKCS9599

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. Does Product 434760, Benzamidine hydrochloride, contain waters of hydration?

    Sigma-Aldrich does not measure the water content directly of this product. However, based on the way the material is produced and handled, we would not expect any waters of hydration to be present. The corresponding hydrate product is found under Product No. B6506.

  6. What is Product 434760, Benzamidine hydrochloride, soluble in?

    We would expect benzamidine hydrochloride to be soluble in water to at least 50 mg/mL. However, gentle heating may be required to solubilize it at this concentration.

  7. What can Product 434760, Benzamidine hydrochloride, be used for?

    Benzamidine hydrochloride has been shown to act as a reversible inhibitor of trypsin, trypsin-like enzymes and serine proteases.

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Seweryn Mroczek et al.
Nature communications, 8(1), 619-619 (2017-09-22)
FAM46C is one of the most frequently mutated genes in multiple myeloma. Here, using a combination of in vitro and in vivo approaches, we demonstrate that FAM46C encodes an active non-canonical poly(A) polymerase which enhances mRNA stability and gene expression.
Bradley S Heater et al.
Biotechnology for biofuels, 12, 165-165 (2019-07-13)
We have recently developed a one-step, genetically encoded immobilization approach based on fusion of a target enzyme to the self-crystallizing protein Cry3Aa, followed by direct production and isolation of the fusion crystals from Bacillus thuringiensis. Using this approach, Bacillus subtilis
Zaofeng Yang et al.
iScience, 23(6), 101158-101158 (2020-05-29)
The effectiveness of cancer radiotherapy is frequently hindered by the hypoxia of the tumor microenvironment. Direct delivery of oxygen to hypoxic tumor tissues is an attractive strategy to overcome this hypoxia-associated radioresistance. Herein, we report the generation of submicron-sized particles
Joris Van Lindt et al.
Communications biology, 4(1), 77-77 (2021-01-21)
Understanding the kinetics, thermodynamics, and molecular mechanisms of liquid-liquid phase separation (LLPS) is of paramount importance in cell biology, requiring reproducible methods for studying often severely aggregation-prone proteins. Frequently applied approaches for inducing LLPS, such as dilution of the protein
Anita de Ruiter et al.
Journal of computational chemistry, 34(12), 1024-1034 (2013-01-22)
The performances of Bennett's acceptance ratio method and thermodynamic integration (TI) for the calculation of free energy differences in protein simulations are compared. For the latter, the standard trapezoidal rule, Simpson's rule, and Clenshaw-Curtis integration are used as numerical integration
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