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Merck
CN

42754

Supelco

Ginsenoside Rk1

analytical standard

别名:

(3β, 12β)-12-Hydroxydammara-20,24-dien-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside

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About This Item

经验公式(希尔记法):
C42H70O12
分子量:
767.00
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

方案

≥95.0% (HPLC)

保质期

limited shelf life, expiry date on the label

包装形式

neat

储存温度

2-8°C

SMILES字符串

CC1(C)[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)CC[C@@]4(C)[C@@]1([H])CC[C@]5(C)[C@]4([H])C[C@@H](O)[C@@]6([H])[C@@]5(C)CC[C@@]6(C(CCC=C(C)C)=C)[H]

InChI

1S/C42H70O12/c1-21(2)10-9-11-22(3)23-12-16-42(8)30(23)24(45)18-28-40(6)15-14-29(39(4,5)27(40)13-17-41(28,42)7)53-38-36(34(49)32(47)26(20-44)52-38)54-37-35(50)33(48)31(46)25(19-43)51-37/h10,23-38,43-50H,3,9,11-20H2,1-2,4-8H3/t23-,24-,25-,26-,27+,28-,29+,30

InChI key

KWDWBAISZWOAHD-MHOSXIPRSA-N

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一般描述

Ginsenoside Rk1 is the major bioactive component isolated from heat-processed Panax ginseng Meyer (ginseng) plants. It is a monomeric compound that has been reported to exhibit anti-inflammatory, anti-allergic, and anti-tumor properties and is utilized for the treatment of cancer and diabetes mellitus.

应用

Ginsenoside Rk1 may be used as an analytical reference standard for the determination of the analyte in Panax ginseng preparations and Chinese medicine formula Sheng-Mai San (SMS) and rat plasma samples (post administration of SMS) by chromatography techniques.

其他说明

This compound is commonly found in plants of the genus: panax

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Anti-tumor activity of the ginsenoside Rk1 in human hepatocellular carcinoma cells through inhibition of telomerase activity and induction of apoptosis
Kim YJ, et al.
Biological & Pharmaceutical Bulletin, 31(5), 826-830 (2008)
Simultaneous determination of 30 ginsenosides in Panax ginseng preparations using ultra performance liquid chromatography
Park HW, et al.
Journal of ginseng research, 37(4), 457-457 (2013)
Ginsenoside Rk1 suppresses pro-inflammatory responses in lipopolysaccharide-stimulated RAW264. 7 cells by inhibiting the Jak2/Stat3 pathway
Qian YU, et al.
Chinese Journal of Natural Medicines, 15(10), 751-757 (2017)
Identification of multiple constituents in the traditional Chinese medicine formula Sheng-Mai San and rat plasma after oral administration by HPLC-DAD-MS/MS
Wang YH, etal.
Journal of Pharmaceutical and Biomedical Analysis, 54(5), 1110-1127 (2011)
Simultaneous quantification of 14 ginsenosides in Panax ginseng CA Meyer (Korean red ginseng) by HPLC-ELSD and its application to quality control.
Kim NS, et al.
Journal of Pharmaceutical and Biomedical Analysis, 45(1), 164-170 (2007)

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