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Merck
CN

424455

Sigma-Aldrich

Resorufin

Dye content 95 %

别名:

7-羟基-3H-吩恶嗪-3-酮, NSC 12097

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About This Item

经验公式(希尔记法):
C12H7NO3
CAS号:
分子量:
213.19
Beilstein:
174850
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47

表单

powder

质量水平

组成

Dye content, 95%

mp

>300 °C (lit.)

λmax

573 nm

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

O=C(C=C1)C=C2C1=NC3=CC=C(O)C=C3O2

InChI

1S/C12H7NO3/c14-7-1-3-9-11(5-7)16-12-6-8(15)2-4-10(12)13-9/h1-6,14H

InChI key

HSSLDCABUXLXKM-UHFFFAOYSA-N

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一般描述

试卤灵,一种可用于直接观察细胞呼吸的氧化还原探针。它具有高荧光性,最大激发波长为563nm,最大发射波长为587nm。

应用

试卤灵已被用于测量过氧化氢的产生。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Yutaka Hitomi et al.
Analytical chemistry, 83(24), 9213-9216 (2011-11-18)
We developed a metal-based fluorescent probe for H(2)O(2) called MBFh1, which has an iron complex as a reaction site for H(2)O(2) and a 3,7-dihydroxyphenoxazine derivative as the fluorescent reporter unit. The iron complex reacts quickly with H(2)O(2) to form oxidants
Malena B Rone et al.
Molecular endocrinology (Baltimore, Md.), 26(11), 1868-1882 (2012-09-14)
Steroid hormones are critical for organismal development and health. The rate-limiting step in steroidogenesis is the transport of cholesterol from the outer mitochondrial membrane (OMM) to the cytochrome P450 enzyme CYP11A1 in the inner mitochondrial membrane (IMM). Cholesterol transfer occurs
Ahmed A El-Sherbeni et al.
Drug metabolism and disposition: the biological fate of chemicals, 42(9), 1498-1507 (2014-06-28)
Cytochrome P450 (P450) enzymes mediate arachidonic acid (AA) oxidation to several biologically active metabolites. Our aims in this study were to characterize AA metabolism by different recombinant rat P450 enzymes and to identify new targets for modulating P450-AA metabolism in
Karsten Klopffleisch et al.
Acta crystallographica. Section D, Biological crystallography, 68(Pt 8), 883-892 (2012-08-08)
A low-resolution structure of the catalytic subunit CK2α of human protein kinase CK2 (formerly known as casein kinase 2) in complex with the ATP-competitive inhibitor resorufin is presented. The structure supplements previous human CK2α structures in which the interdomain hinge/helix
Hubert M Piwonski et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(22), E1437-E1443 (2012-05-09)
Enzymatic inhibition by product molecules is an important and widespread phenomenon. We describe an approach to study product inhibition at the single-molecule level. Individual HRP molecules are trapped within surface-tethered lipid vesicles, and their reaction with a fluorogenic substrate is

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