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等级
analytical standard
质量水平
检测方案
≥99% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
>300 °C (lit.)
应用
food and beverages
格式
neat
储存温度
2-8°C
SMILES字符串
Oc1ccc(cc1)C2=CC(=O)c3c(O)cc(O)cc3O2
InChI
1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H
InChI key
KZNIFHPLKGYRTM-UHFFFAOYSA-N
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一般描述
黄酮类化合物属于多酚类化合物。在抑制肿瘤生长和化学预防等生物活性中起关键作用。芹菜素是一种植物类黄酮，多用于抑制鸟氨酸脱羧酶活性和皮肤肿瘤。
应用
LC-ESI-MS/MS 可作为内标物，用于测定大鼠血液和尿液中的飞燕草苷及其代谢产物。
有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务。
生化/生理作用
一种植物类黄酮，研究发现它通过在G2/M阶段阻止细胞周期来抑制细胞增殖。通过细胞周期停滞和诱导凋亡来抑制生长似乎与p53的诱导有关。通过抑制蛋白激酶C和由此导致的癌基因表达抑制来抑制PMA介导的肿瘤促进。研究还报道了抑制拓扑异构酶ⅰ催化的脱氧核糖核酸再连接和增强间隙连接细胞间通讯。
包装
无底玻璃瓶。内含物在插入的融合锥体内。
WGK
WGK 3
Determination of the metabolite content of Brassica juncea cultivars using comprehensive two-dimensional liquid chromatography coupled with a photodiode array and mass spectrometry detection
Arena K, et al.
Molecules (Basel), 25(5), 1235-1235 (2020)
Lingling Pang et al.
International journal of clinical and experimental pathology, 12(10), 3700-3709 (2020-01-15)
The purpose of this study was to investigate the anti-inflammatory potential of the natural flavonoid apigenin to mitigate the airway inflammation in asthmatic mice exposed to particulate matter (PM) 2.5, and examine the possible mechanisms involved. BALB/c mice were sensitized
Flavonoids apigenin and quercetin inhibit melanoma growth and metastatic potential.
Caltagirone S
International Journal of Cancer. Journal International Du Cancer, 87(4), 595-600 (2000)
Identification of puerarin and its metabolites in rats by liquid chromatography-tandem mass spectrometry.
Prasain JK
Journal of Agricultural and Food Chemistry, 52(12), 3708-3712 (2004)
Sivaprakasam Balasubramanian et al.
Toxicology and applied pharmacology, 224(3), 214-219 (2007-05-12)
We have proposed that it is important to examine the impact of chemopreventive agents on the function of normal human epidermal keratinocytes since these cells comprise the barrier that protects the body from a range of environmental insults. In this
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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