所有图片(1)
别名:
5-OH-DCF, 2-[(2,6-Dichlorophenyl)amino]-5-hydroxybenzeneacetic acid
经验公式（希尔记法）:
C14H11Cl2NO3
CAS号:
分子量:
312.15
Beilstein:
4199419
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.24
推荐产品
等级
analytical standard
质量水平
检测方案
≥97.0% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
pharmaceutical
格式
neat
储存温度
−20°C
SMILES字符串
OC(CC1=CC(O)=CC=C1NC2=C(Cl)C=CC=C2Cl)=O
InChI
1S/C14H11Cl2NO3/c15-10-2-1-3-11(16)14(10)17-12-5-4-9(18)6-8(12)7-13(19)20/h1-6,17-18H,7H2,(H,19,20)
InChI key
VNQURRWYKFZKJZ-UHFFFAOYSA-N
相关类别
一般描述
5-Hydroxydiclofenac, a monohydroxylated metabolite of diclofenac, belongs to the class of non-steroidal anti-inflammatory compounds.29}
应用
5-Hydroxydiclofenac may be used as an analytical standard for the determination of the analyte in biological samples and wastewater by liquid chromatography (LC) based techniques.
推荐产品
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警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Simultaneous determination of diclofenac, its human metabolites and microbial nitration/nitrosation transformation products in wastewaters by liquid chromatography/quadrupole-linear ion trap mass spectrometry
Osorio V, et al.
Journal of Chromatography A, 1347(1), 63-71 (2014)
High-performance liquid chromatographic determination of diclofenac and its monohydroxylated metabolites in biological fluids
Godbillon J, et al.
Journal of Chromatography. B, Biomedical Applications, 338(1), 151-159 (1985)
Jing Shi et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 191, 1-7 (2017-10-02)
A novel flow injection chemiluminescence immunoassay for simple, sensitive and low-cost detection of diclofenac was established based on specific binding of antigen and antibody. Carboxylic resin beads used as solid phase carrier materials provided good biocompatibility and large surface-to-volume ratio
Simon T K Yauw et al.
Surgical infections, 19(4), 417-423 (2018-04-07)
The non-steroidal anti-inflammatory drug diclofenac has been associated with intestinal anastomotic leakage, although the underlying pathophysiology is unclear. Previous data suggest that reactivation of biliary diclofenac metabolites by microbial β-glucuronidases in the gut plays a role in harming the intestinal
Anna Raysyan et al.
Analytical and bioanalytical chemistry, 413(4), 999-1007 (2020-11-27)
Pharmacologically active compounds are often detected in wastewater and surface waters. The nonsteroidal anti-inflammatory drug diclofenac (DCF) was included in the European watch list of substances that requires its environmental monitoring in the member states. DCF may harmfully influence the
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