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等级
analytical standard
质量水平
方案
≥97.0% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
pharmaceutical
包装形式
neat
储存温度
−20°C
SMILES字符串
OC(CC1=CC(O)=CC=C1NC2=C(Cl)C=CC=C2Cl)=O
InChI
1S/C14H11Cl2NO3/c15-10-2-1-3-11(16)14(10)17-12-5-4-9(18)6-8(12)7-13(19)20/h1-6,17-18H,7H2,(H,19,20)
InChI key
VNQURRWYKFZKJZ-UHFFFAOYSA-N
相关类别
一般描述
5-Hydroxydiclofenac, a monohydroxylated metabolite of diclofenac, belongs to the class of non-steroidal anti-inflammatory compounds.29}
应用
5-Hydroxydiclofenac may be used as an analytical standard for the determination of the analyte in biological samples and wastewater by liquid chromatography (LC) based techniques.
推荐产品
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Simultaneous determination of diclofenac, its human metabolites and microbial nitration/nitrosation transformation products in wastewaters by liquid chromatography/quadrupole-linear ion trap mass spectrometry
Osorio V, et al.
Journal of Chromatography A, 1347(1), 63-71 (2014)
High-performance liquid chromatographic method for the routine determination of diclofenac and its hydroxy and methoxy metabolites from in vitro systems
Schmitz G, et al.
Journal of Chromatography. B, Biomedical Applications, 620(1), 158-163 (1993)
Klaudia Świacka et al.
Marine pollution bulletin, 141, 249-255 (2019-04-09)
Interest in the presence of pharmaceutically active compounds in the aquatic environment has been growing for over 20 years, yet very few studies deal with the metabolism of pharmaceuticals in marine organisms. In this study, the bioaccumulation under short-term conditions and
Jing Shi et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 191, 1-7 (2017-10-02)
A novel flow injection chemiluminescence immunoassay for simple, sensitive and low-cost detection of diclofenac was established based on specific binding of antigen and antibody. Carboxylic resin beads used as solid phase carrier materials provided good biocompatibility and large surface-to-volume ratio
High-performance liquid chromatographic determination of diclofenac and its monohydroxylated metabolites in biological fluids
Godbillon J, et al.
Journal of Chromatography. B, Biomedical Applications, 338(1), 151-159 (1985)
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