41244
N-Desmethyl ofloxacin
analytical standard
别名:
9-Fluoro-2,3-dihydro-3-methyl-10-(1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
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关于此项目
经验公式（希尔记法）:
C17H18FN3O4
化学文摘社编号:
分子量:
347.34
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
4890029
产品名称
N-Desmethyl ofloxacin, analytical standard
InChI key
WKRSSAPQZDHYRV-UHFFFAOYSA-N
InChI
1S/C17H18FN3O4/c1-9-8-25-16-13-10(15(22)11(17(23)24)7-21(9)13)6-12(18)14(16)20-4-2-19-3-5-20/h6-7,9,19H,2-5,8H2,1H3,(H,23,24)
grade
analytical standard
assay
≥96.5% (HPLC)
shelf life
limited shelf life, expiry date on the label
mp
256-262 °C
application(s)
clinical testing
format
neat
Quality Level
Application
N-Desmethyl ofloxacin may be used as an analytical reference standard for the determination of the analyte in biological samples by high-pressure liquid chromatography with fluorescence detection and capillary electrophoresis using laser-induced fluorescence detection technique.
General description
N-Desmethyl ofloxacin is one of the active metabolites of ofloxacin, a drug prescribed for treating bacterial infections (effective against both Gram-positive and Gram-negative bacteria) that acts by inhibiting the enzyme DNA gyrase.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Kinetics of ofloxacin and its metabolites in cerebrospinal fluid after a single intravenous infusion of 400 milligrams of ofloxacin.
Nau R, et al.
Antimicrobial Agents and Chemotherapy, 38(8), 1849-1853 (1994)
Stereoselective determination of ofloxacin and its metabolites in human urine by capillary electrophoresis using laser-induced fluorescence detection
Horstkotter C and Blaschke G
Journal of Chromatography. B, Biomedical Sciences and Applications, 754(1), 169-178 (2001)
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