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线性分子式:
(CH3)2NCH(OC2H5)2
化学文摘社编号:
分子量:
147.22
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
214-707-9
Beilstein/REAXYS Number:
741889
MDL number:
产品名称
N,N-二甲基甲酰胺二乙缩醛, for esterification of fatty acids, ≥95.0% (GC)
InChI key
BWKAYBPLDRWMCJ-UHFFFAOYSA-N
InChI
1S/C7H17NO2/c1-5-9-7(8(3)4)10-6-2/h7H,5-6H2,1-4H3
SMILES string
CCOC(OCC)N(C)C
assay
≥95.0% (GC)
quality
for esterification of fatty acids
color
colorless to yellow
refractive index
n20/D 1.397-1.401
n20/D 1.400 (lit.)
bp
130-133 °C (lit.)
density
0.859 g/mL at 25 °C (lit.)
functional group
amine
ether
Quality Level
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General description
N,N-Dimethylformamide diethyl acetal undergoes Me3SiCl-mediated three-component coupling reaction with alkyne to yield 2,3,4,5-tetrasubstituted pyridine derivatives.
N,N-Dimethylformamide diethyl acetal (DMF diethyl acetal) on reaction with butanol affords N,N-dimethylformamide dibutyl acetal. It participates in various alkylation, formylation, and aminomethylenation reactions. It has been synthesized from N,N-dialkyl(chloromethylene)ammonium chloride.
Other Notes
用于脂肪酸的酯化反应的试剂;综述
Application
N,N-Dimethylformamide diethyl acetal is a suitable reagent for the esterification of fatty acids. It is suitable reagent used in the quantification of cocaine and its primary metabolite, benzoyl ecgonine, from a urine matrix by gas chromatography.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Flam. Liq. 3
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
82.4 °F - closed cup
flash_point_c
28 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
N,N-Dimethylformamide Diethyl Acetal.
Pindur U.
e-EROS Encyclopedia of Reagents for Organic Synthesis. (2001)
J.P. Thenot et al.
Analytical Letters, 217-217 (1972)
DeWolfe RH.
Carboxylic Ortho Acid Derivatives: Preparation and Synthetic Applications (Academic press), 14, 424-424 (2012)
Toshiaki Sasada et al.
The Journal of organic chemistry, 73(17), 6905-6908 (2008-07-30)
We have identified a Me3SiCl-mediated three-component coupling reaction of a functionalized enamine, N,N-dimethylformamide diethyl acetal, and an internal alkyne having an electron-withdrawing group that produces 2,3,4,5-tetrasubstituted pyridine derivatives in good to excellent yields via a single-step reaction.
N C Jain et al.
Journal of forensic sciences, 22(1), 7-16 (1977-01-01)
A gas chromatographic procedure has been developed for the simultaneous determination of cocaine and benzoyl ecgonine in urine specimens. The two drugs are extracted by isopropanol/chloroform from urine samples saturated with a bisalt buffer. The organic extract is evaporated to
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