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安全信息

39961

Supelco

大麻二酚酸

analytical standard

别名:

CBDA

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About This Item

经验公式（希尔记法）:
C22H30O4
CAS号:
1244-58-2
分子量:
358.47
MDL编号:
MFCD09838337
UNSPSC代码:
41116107
NACRES:
NA.24

等级

analytical standard

质量水平

100

方案

≥95% (HPLC)

保质期

limited shelf life, expiry date on the label

药品控制

USDEA Schedule I; Home Office Schedule 1; regulated under CDSA - not available from Sigma-Aldrich Canada

技术

HPLC: suitable
gas chromatography (GC): suitable
solid phase extraction (SPE): suitable

适用性

in accordance for H-NMR

应用

forensics and toxicology
pharmaceutical (small molecule)
veterinary

包装形式

neat

储存温度

−20°C

SMILES字符串

CCCCCc1cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c(O)c1C(O)=O

InChI

1S/C22H30O4/c1-5-6-7-8-15-12-18(23)20(21(24)19(15)22(25)26)17-11-14(4)9-10-16(17)13(2)3/h11-12,16-17,23-24H,2,5-10H2,1,3-4H3,(H,25,26)/t16-,17+/m0/s1

InChI key

WVOLTBSCXRRQFR-DLBZAZTESA-N

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一般描述

Cannabidiolic acid belongs to the group of cannabinoids, a class of psychoactive and non-psychoactive compounds produced in the Cannabis (marijuana) plant. It is an acidic precursor,(4) which shows potential therapeutic efficacy in the treatment of pain, mood disorders, and inflammatory diseases.

应用

Cannabidiolic acid has been used as an analytical standard for the quantification of the analyte in biomass, extracts of different varieties of cannabis, and commercial cannabis products using chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

象形图

Health hazardExclamation mark
GHS08,GHS07

警示用语：

Warning

危险声明

H302,H361d

危险分类

Acute Tox. 4 Oral - Repr. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品

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分析证书(COA)

Lot/Batch Number
BCCM1260
BCCL7480
BCCH7605
BCCG0971
BCCF3880

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Shuso Takeda et al.
Drug metabolism and disposition: the biological fate of chemicals, 36(9), 1917-1921 (2008-06-17)
In the present study it was revealed that cannabidiolic acid (CBDA) selectively inhibited cyclooxygenase (COX)-2 activity with an IC(50) value (50% inhibition concentration) around 2 microM, having 9-fold higher selectivity than COX-1 inhibition. In contrast, Delta(9)-tetrahydrocannabinolic acid (Delta(9)-THCA) was a
D Bolognini et al.
British journal of pharmacology, 168(6), 1456-1470 (2012-11-06)
To evaluate the ability of cannabidiolic acid (CBDA) to reduce nausea and vomiting and enhance 5-HT(1A) receptor activation in animal models. We investigated the effect of CBDA on (i) lithium chloride (LiCl)-induced conditioned gaping to a flavour (nausea-induced behaviour) or
Commercial cannabis consumer products part 2: HPLC-DAD quantitative analysis of cannabis cannabinoids
Ciolino aL, et al.
Forensic Science International, 289(6), 438-447 (2018)
Elizabeth M Mudge et al.
Analytical and bioanalytical chemistry, 409(12), 3153-3163 (2017-02-25)
There is an explosion in the number of labs analyzing cannabinoids in marijuana (Cannabis sativa L., Cannabaceae) but existing methods are inefficient, require expert analysts, and use large volumes of potentially environmentally damaging solvents. The objective of this work was
Roger G Pertwee et al.
British journal of pharmacology, 175(1), 100-112 (2017-10-24)
The aim of this study was to compare the abilities of cannabidiolic acid methyl ester (HU-580) and cannabidiolic acid (CBDA) to enhance 5-HT We investigated the effects of HU-580 and CBDA on (i) activation by 8-hydroxy-2-(di-n-propylamino)tetralin of human 5-HT HU-580
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