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蒸汽密度
3.6 (vs air)
质量水平
蒸汽压
5 mmHg ( 20 °C)
等级
purum
方案
≥98.0% (GC)
表单
liquid
杂质
≤2% water
折射率
n20/D 1.435 (lit.)
n20/D 1.436
沸点
133 °C (lit.)
密度
0.812 g/mL at 25 °C (lit.)
官能团
amine
SMILES字符串
CN(C)CCCN
InChI
1S/C5H14N2/c1-7(2)5-3-4-6/h3-6H2,1-2H3
InChI key
IUNMPGNGSSIWFP-UHFFFAOYSA-N
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一般描述
3-(Dimethylamino)-1-propylamine (DMAPA, N,N-dimethyl-1,3-propanediamine) is a dialkylamino alkyl amine. It has been prepared from dimethylamine and acrylonitrile and confirmed by 1H NMR. It participates in the synthesis of bio-based zwitterionic surfactants from waste cooking oil (WCO).
应用
3-(Dimethylamino)-1-propylamine (DMAPA) is suitable reagent used in the following studies:
- As a cationic moiety to form the ionic liquid, 3-(dimethylamino)-1-propylaminium formate ([DMAPA]FA) which is a potential reagent to extract protein from yeast cells.
- As an aminating agent in the palladium-catalyzed amination of aryl amines.
- In the derivatization of pullulan to form cationic pullulan.
- In the partial modification of poly(styrene-alt-maleic anhydride) to form N-substituted maleimide.
- As a test compound in the parallel synthesis of alkylamine lipidoids.
- To cleave the polyamides synthesized by solid phase methods on Boc-β-Ala-PAM resin.
- Synthesis of (N,N-dialkylamino)alkyl-2-amino benzamide by reacting with isatoic anhydride.
- As a reagent for the anomeric deacetylation of protected sugars.
- Preparation of bioreducible copolymers used in gene delivery.
其他说明
工业用途
警示用语：
Danger
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
靶器官
Respiratory system
储存分类代码
3 - Flammable liquids
WGK
WGK 1
闪点(°F)
89.6 °F - closed cup
闪点(°C)
32 °C - closed cup
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
危险化学品
Dhananjay Jere et al.
Biomedical materials (Bristol, England), 4(2), 025020-025020 (2009-04-08)
Bioreducible disulfide linkage-employing drug conjugate has already been approved for drug delivery application, and also has shown immense potential in gene and siRNA transfection. This paper will focus on the recent developments in bioreducible polymeric systems for gene and siRNA
DNA complexation by cationic pullulan possessing thermo-sensitive units.
Constantin M, et al.
Digest Journal of Nanomaterials and Biostructures, 6, 849-861 (2011)
Permanently antimicrobial waterborne coatings based on the dual role of modified poly (styrene-co-maleic anhydride).
Cloete WJ, et al
Eur. Polymer J., 49(5), 1080-1088 (2013)
P. Lappe et al.
Chem. Zeit., 111, 117-117 (1987)
New antihistaminic agents: Synthesis and evaluation of h 1-antihistaminic actions of 3-[(N,N-dialkylamino) alkyl)-1, 2, 3, 4-tetrahydro-(1H)-thioquinazolin-4 (3H)-ones and their oxo analogues.
Raju MB, et al
Indian Journal of Pharmaceutical Sciences, 69(6), 853-853 (2007)
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