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About This Item
经验公式（希尔记法）:
C8H4K2O12Sb2 · 3H2O
CAS号:
分子量:
667.87
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.21
方案:
≥99%
99.0-103.0%
99.0-103.0%
等级:
ACS reagent
表单:
powder
溶解性:
water: soluble
推荐产品
等级
ACS reagent
质量水平
方案
≥99%
99.0-103.0%
表单
powder
杂质
≤0.020 meq/g Titr. acid or base
缺失
≤2.7% loss on drying
mp
≥300 °C (lit.)
溶解性
water: soluble
痕量阳离子
As: ≤0.015%
SMILES字符串
O.O.O.[K+].[K+].O=C1O[Sb-]23OC1C4O[Sb-]5(OC(C(O2)C(=O)O3)C(=O)O5)OC4=O
InChI
1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4
InChI key
WBTCZEPSIIFINA-UHFFFAOYSA-J
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一般描述
酒石酸锑钾是锑的三价金属盐。酒石酸锑钾 (PAT) 是一种抗寄生虫药 ，主要用于治疗利什曼原虫引起的感染。它在非小细胞肺癌 (NSCLC) 细胞中的抗血管生成和抗肿瘤属性已被研究。对中国仓鼠卵巢细胞的研究显示，它可以阻止 γ-辐照。
应用
酒石酸锑钾三水合物可用于在去离子水 (100 mg/L) 中制备锑 (Sb (III)) 贮备液。也可用于干沉积物中总磷的分光光度测定。
酒石酸锑钾三水合物已用于剂量抑制实验，以评价含锑的抗利什曼原虫化合物对培养基 199 中利什曼原虫前鞭毛体的剂量抑制曲线。
警示用语：
Danger
危险分类
Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
危险化学品
v
Vijayaraghavan K and Balasubramanian R.
Industrial & Engineering Chemistry Research, 50(17), 9864-9869 (2011)
Nutrient contents in bottom sediment samples from a southern Brazilian microbasin.
Antunes M, et al.
Environmental earth sciences, 69(3), 959-968 (2013)
Reduced Antimony Accumulation in ARM58-Overexpressing Leishmania infantum.
Schafer C, et al.
Antimicrobial Agents and Chemotherapy, 58(3), 1565-1574 (2014)
Susan Wyllie et al.
Biochemical pharmacology, 71(3), 257-267 (2005-12-02)
Trivalent antimonial compounds (Sb(III)), originally used in the treatment of leishmaniasis, are now being proposed as a novel therapy for acute promyelocytic leukaemia (APL). Here, we examine the effects of Sb(III) and pentavalent antimonial drugs (Sb(V)) on glutathione homeostasis, oxidative
Daniel B Liarte et al.
Parasitology research, 107(1), 205-212 (2010-04-08)
In the present study, we selected in vitro populations of Leishmania Viannia guyanensis, L.V. braziliensis, L. Leishmania amazonensis and L.L. infantum chagasi that were resistant to potassium antimony tartrate (SbIII). The resistance index of these populations varied from 4- to
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