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Merck
CN

38332

Supelco

东莨菪内酯

analytical standard

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别名:
6-甲氧基伞形酮, 7-羟基-6-甲氧基-2H-1-苯并吡喃-2-酮, 7-羟基-6-甲氧基香豆素, 七叶亭-6-甲醚, 东莨菪亭, 东莨菪内酯, 柯阿托酸, 莨菪亭, 钩吻酸
经验公式(希尔记法):
C10H8O4
CAS号:
分子量:
192.17
Beilstein:
156296
EC 号:
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

检测方案

≥97.0% (HPLC)

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

203-205 °C (lit.)

应用

food and beverages

格式

neat

储存温度

2-8°C

SMILES字符串

COc1cc2C=CC(=O)Oc2cc1O

InChI

1S/C10H8O4/c1-13-9-4-6-2-3-10(12)14-8(6)5-7(9)11/h2-5,11H,1H3

InChI key

RODXRVNMMDRFIK-UHFFFAOYSA-N

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一般描述

Scopoletin is a coumarin compound and pharmacologically active chemical that is found in various plant species.

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Scopoletin may be used as a reference standard for the determination of scopoletin in:
  • Roots, stems, branches, and seeds as well as leaves of Chimonanthus nitens Oliv. by ultra-high performance liquid chromatography/tandem quadrupole-time-of-flight mass spectrometry (UHPLC-QTOF-MS/MS) equipped with modified mass deflect filter or diagnostic product ions/neutral loss filter.
  • Canscora decussate (South Indian Shankhpushpi) extracts by high performance thin layer chromatography (HPTLC).
  • Morinda tinctoria Roxb. leaf by HPTLC in conjunction with HPLC and gas chromatography with MS.

生化/生理作用

东莨菪素通过促进 LPL 基因的转录,显著增强脂肪细胞中脂蛋白脂肪酶的活性。它还部分逆转 TNF-α 对 LPL 的抑制作用。

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

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Comprehensive profiling and characterization of coumarins from roots, stems, leaves, branches, and seeds of Chimonanthus nitens Oliv. using ultra-performance liquid chromatography/quadrupole-time-of-flight mass spectrometry combined with modified mass defect filter.
Tan T, et al.
Journal of Pharmaceutical and Biomedical Analysis, 141(2-3), 140-148 (2017)
Structural characterization and discrimination of Chimonanthus nitens Oliv. leaf from different geographical origins based on multiple chromatographic analysis combined with chemometric methods.
Huang WP, et al.
Journal of Pharmaceutical and Biomedical Analysis, 154(2-3), 236-244 (2018)
HPTLC Finger print analysis and Phytochemical Investigation of Morinda tinctoria Roxb. Leaf extracts by HPLC and GS MS.
Arunachalam KD, et al.
International Journal of Pharmacy and Pharmaceutical Sciences, 7(2), 360-366 (2015)
Xiujuan Yao et al.
International immunopharmacology, 14(4), 454-462 (2012-08-24)
The present study determined the anti-inflammatory activity of scopoletin in gout air pouch model and revealed the underlying mechanisms by in vitro assays. Monosodium urate (MSU) crystal-induced inflammation in mouse air pouch model, an experimental model for acute gout, was
Shakti Deep Pachauri et al.
Journal of ethnopharmacology, 139(1), 34-41 (2011-11-24)
Noni (Morinda citrifolia L.) is widely used for different illnesses including CNS disorders. Recently Noni has been reported to prevent amyloid beta induced memory impairment in mice. However, the influence of Noni on cholinergic system has not been explored so

实验方案

HPTLC fingerprinting enables rapid identification of passion flower with related reference materials.

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