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等级
analytical standard
质量水平
检测方案
≥97.0% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
203-205 °C (lit.)
应用
food and beverages
格式
neat
储存温度
2-8°C
SMILES字符串
COc1cc2C=CC(=O)Oc2cc1O
InChI
1S/C10H8O4/c1-13-9-4-6-2-3-10(12)14-8(6)5-7(9)11/h2-5,11H,1H3
InChI key
RODXRVNMMDRFIK-UHFFFAOYSA-N
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一般描述
Scopoletin is a coumarin compound and pharmacologically active chemical that is found in various plant species.
应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Scopoletin may be used as a reference standard for the determination of scopoletin in:
- Roots, stems, branches, and seeds as well as leaves of Chimonanthus nitens Oliv. by ultra-high performance liquid chromatography/tandem quadrupole-time-of-flight mass spectrometry (UHPLC-QTOF-MS/MS) equipped with modified mass deflect filter or diagnostic product ions/neutral loss filter.
- Canscora decussate (South Indian Shankhpushpi) extracts by high performance thin layer chromatography (HPTLC).
- Morinda tinctoria Roxb. leaf by HPTLC in conjunction with HPLC and gas chromatography with MS.
生化/生理作用
东莨菪素通过促进 LPL 基因的转录,显著增强脂肪细胞中脂蛋白脂肪酶的活性。它还部分逆转 TNF-α 对 LPL 的抑制作用。
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Comprehensive profiling and characterization of coumarins from roots, stems, leaves, branches, and seeds of Chimonanthus nitens Oliv. using ultra-performance liquid chromatography/quadrupole-time-of-flight mass spectrometry combined with modified mass defect filter.
Journal of Pharmaceutical and Biomedical Analysis, 141(2-3), 140-148 (2017)
Structural characterization and discrimination of Chimonanthus nitens Oliv. leaf from different geographical origins based on multiple chromatographic analysis combined with chemometric methods.
Journal of Pharmaceutical and Biomedical Analysis, 154(2-3), 236-244 (2018)
HPTLC Finger print analysis and Phytochemical Investigation of Morinda tinctoria Roxb. Leaf extracts by HPLC and GS MS.
International Journal of Pharmacy and Pharmaceutical Sciences, 7(2), 360-366 (2015)
Inhibition of monosodium urate crystal-induced inflammation by scopoletin and underlying mechanisms.
International immunopharmacology, 14(4), 454-462 (2012-08-24)
The present study determined the anti-inflammatory activity of scopoletin in gout air pouch model and revealed the underlying mechanisms by in vitro assays. Monosodium urate (MSU) crystal-induced inflammation in mouse air pouch model, an experimental model for acute gout, was
Journal of ethnopharmacology, 139(1), 34-41 (2011-11-24)
Noni (Morinda citrifolia L.) is widely used for different illnesses including CNS disorders. Recently Noni has been reported to prevent amyloid beta induced memory impairment in mice. However, the influence of Noni on cholinergic system has not been explored so
实验方案
HPTLC fingerprinting enables rapid identification of passion flower with related reference materials.
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