等级
analytical standard
保质期
limited shelf life, expiry date on the label
浓度
~100 μg/mL in acetonitrile
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
cleaning products
cosmetics
food and beverages
personal care
格式
single component solution
储存温度
−20°C
SMILES字符串
CO[C@@H]1[C@@H](CC[C@]2(CO2)C1[C@@]3(C)O[C@@H]3C\C=C(\C)C)OC(=O)\C=C\C=C\C=C\C=C\C(O)=O
InChI
1S/C26H34O7/c1-18(2)13-14-20-25(3,33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28)/b7-5+,8-6+,11-9+,12-10+/t19-,20?,23-,24-,25+,26+/m1/s1
InChI key
NGGMYCMLYOUNGM-IJIYPQOHSA-N
一般描述
Fumagillin is an antibiotic obtained by the fermentation of certain strains of Aspergillus fumigatus with potent amoebicidal action.
应用
Fumagillin may be used as an analytical reference standard for the quantification of the analyte in honey samples and technical materials using various chromatographic techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
警示用语：
Danger
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
WGK
WGK 2
闪点(°F)
35.6 °F
闪点(°C)
2.0 °C
法规信息
高风险级别生物产品--毒素类产品
危险化学品
Yujin Park et al.
Anticancer research, 37(8), 4139-4146 (2017-07-26)
Eribulin mesylate, also called Halaven® (HAL), was recently developed as a microtubule-targeting drug and is used in the clinic for resistant or metastatic cancer. Previously, we showed that P-glycoprotein (P-gp)-overexpressing KBV20C oral cancer cells are highly resistant to HAL compared
Determination of fumagillin by high performance liquid chromatography
Brackett.MJ, et al.
Journal of Agricultural and Food Chemistry, 36(4), 762-764 (1988)
Trace analysis of fumagillin in honey by liquid chromatography-diode array-electrospray ionization mass spectrometry
Nozal.JM, et al.
Journal of Chromatography A, 1190(1-2), 224-231 (2008)
Catherine Z Chen et al.
Antimicrobial agents and chemotherapy, 55(2), 667-675 (2010-11-17)
The human pathogen Giardia lamblia is an anaerobic protozoan parasite that causes giardiasis, one of the most common diarrheal diseases worldwide. Although several drugs are available for the treatment of giardiasis, drug resistance has been reported and is likely to
L Champion et al.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 10(8), 1925-1930 (2010-07-20)
We report 10 cases of intestinal microsporidiosis due to Enterocytozoon bieneusi in renal transplant (RT) recipients who were treated with fumagillin. All patients presented with afebrile subacute diarrhea (median of 2 weeks), associated with abdominal cramps (n = 5), and
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