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Merck
CN
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文件

安全信息

36733

Supelco

(−)-尼古丁

PESTANAL®, analytical standard

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别名:
(−)-1-甲基-2-(3-吡啶基)四氢吡咯, (S)-3-（1-甲基-2-吡咯烷基）吡啶
经验公式（希尔记法）:
C10H14N2
CAS号:
54-11-5
分子量:
162.23
Beilstein:
82109
EC 号:
200-193-3
MDL编号:
MFCD00006369
UNSPSC代码:
41116107
PubChem化学物质编号:
329755481
NACRES:
NA.24

等级

analytical standard

质量水平

100

产品线

PESTANAL®

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

折射率

n20/D 1.5265 (lit.)

密度

1.010 g/mL at 20 °C (lit.)

应用

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

格式

neat

SMILES字符串

CN1CCC[C@H]1c2cccnc2

InChI

1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1

InChI key

SNICXCGAKADSCV-JTQLQIEISA-N

基因信息

human ... CHRNA2(1135) , CHRNA4(1137) , CHRNB2(1141)

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应用

有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务部门。

生化/生理作用

烟碱乙酰胆碱受体激动剂原型；自然产生的异构体。

法律信息

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语：

Danger

危险分类

Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

WGK

WGK 3

闪点(°F)

closed cup

闪点(°C)

closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

监管及禁止进口产品

分析证书(COA)

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Ramkrishna Mehendale et al.
American journal of obstetrics and gynecology, 197(4), 363-363 (2007-10-02)
Excess soluble vascular endothelial growth factor receptor, fms-like tyrosine kinase-1 (sFlt-1), and reduced placental growth factor (PlGF) mediate the genesis of preeclampsia. Cigarette smoking reduces the risk of preeclampsia. We hypothesized that placental secretion of sFlt-1 and PlGF was affected
Kang Li et al.
Annals of translational medicine, 9(9), 805-805 (2021-07-17)
Atherosclerosis is a chronic disease, with smoking being an independent risk factor. Irisin, a factor produced by myocytes, is expected to treat smoking-related arteriosclerosis, however its specific mechanism remains unclear. Forty Apoe-/- mice with nicotine intervention were involved in this
Charles C Horn et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 306(5), R341-R351 (2014-01-17)
Signals from the vestibular system, area postrema, and forebrain elicit nausea and vomiting, but gastrointestinal (GI) vagal afferent input arguably plays the most prominent role in defense against food poisoning. It is difficult to determine the contribution of GI vagal
Pooja Naik et al.
BMC neuroscience, 15, 51-51 (2014-04-24)
Both active and passive tobacco smoke (TS) potentially impair the vascular endothelial function in a causative and dose-dependent manner, largely related to the content of reactive oxygen species (ROS), nicotine, and pro-inflammatory activity. Together these factors can compromise the restrictive
Charles C Horn et al.
American journal of physiology. Gastrointestinal and liver physiology, 298(1), G25-G30 (2009-11-07)
Nausea and emesis are common side effects of gastrointestinal disease. Reports indicate that ghrelin and endocannabinoids, agents that stimulate appetite, also reduce emesis evoked by chemotherapy treatment, which suggests that stimulation of feeding inhibits the emetic system. In the following
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