36030
2,4-二氯-1-硝基苯
purum, ≥98.0% (GC)
别名:
1,3-二氯-4-硝基苯, 不对称硝基间二氯苯
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关于此项目
线性分子式:
Cl2C6H3NO2
化学文摘社编号:
分子量:
192.00
EC Number:
210-248-3
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1451655
MDL number:
InChI key
QUIMTLZDMCNYGY-UHFFFAOYSA-N
InChI
1S/C6H3Cl2NO2/c7-4-1-2-6(9(10)11)5(8)3-4/h1-3H
SMILES string
[O-][N+](=O)c1ccc(Cl)cc1Cl
grade
purum
assay
≥98.0% (GC)
bp
258 °C (lit.)
mp
29-32 °C (lit.), 30-32 °C
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 1B - Muta. 2 - Skin Sens. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
305.6 °F
flash_point_c
152 °C
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Maja Aleksic et al.
Toxicology in vitro : an international journal published in association with BIBRA, 22(5), 1169-1176 (2008-04-29)
A large proportion of allergic skin reactions are considered to be the result of skin exposure to small organic chemicals that possess the intrinsic ability to covalently modify skin proteins, either directly or following activation. In the absence of information
P A Botham et al.
The British journal of dermatology, 117(1), 1-9 (1987-07-01)
The fate of 2,4-dinitrochlorobenzene, a potent contact sensitizing chemical, and 2,4-dichloronitrobenzene, a non-sensitizer, was compared following their application to the skin of BALB/c mice. Although both chemicals were able to bind to protein in vitro and were capable of being
Makoto Ohnishi et al.
The Journal of toxicological sciences, 34(2), 233-237 (2009-04-02)
Oral administration of 2,4-dichloro-1-nitrobenzene (2,4-DCNB) causes kidney tumors in the rat. The objective of the present study was to identify the chemical structure of 2,4-DCNB metabolites in urine. Urine from 2,4-DCNB fed rats was more yellow than urine from control
Contribution of caffeine and flavanols in the induction of hepatic Phase II activities by green tea.
A Bu-Abbas et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 36(8), 617-621 (1998-09-12)
Aqueous extracts of green tea, at concentrations of 2.5. 5.0 and 7.5%, were administered to rats as the sole drinking fluid for 4 weeks. Hepatic glutathione S-transferase (GST) activity, determined using 1-chloro-2,4-dinitrobenzene (CDNB) and 3,4-dichloronitrobenzene (DCNB) as substrates, and UDP-glucuronosyl
Hirokazu Kano et al.
Archives of toxicology, 86(11), 1763-1772 (2012-06-26)
Carcinogenicity and chronic toxicity of 2,4-dichloro-1-nitrobenzene (2,4-DCNB) were examined by dietary administration to F344/DuCrj rats and Crj:BDF(1) mice of both sexes for 2 years. Dietary administration commenced when the animals were 6 weeks old. The dietary concentration of 2,4-DCNB was 0 (control)
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