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蒸汽压
0.4 mmHg ( 20 °C)
质量水平
等级
puriss.
方案
≥99.0% (GC)
表单
liquid
折射率
n20/D 1.456 (lit.)
n20/D 1.457
沸点
65-67 °C/15 mmHg (lit.)
mp
−47 °C (lit.)
密度
1.22 g/mL at 25 °C (lit.)
官能团
chloro
ether
SMILES字符串
ClCCOCCCl
InChI
1S/C4H8Cl2O/c5-1-3-7-4-2-6/h1-4H2
InChI key
ZNSMNVMLTJELDZ-UHFFFAOYSA-N
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一般描述
Bis(2-chloroethyl) ether is a chemical intermediate. 2-Chloroethyl β-D-glucosiduronic acid is the major metabolite of bis(2-chloroethyl)ether.
应用
Bis(2-chloroethyl) ether may be used as a solvent and soil fumigant. It may be used in the preparation of macrocyclic polyethers, dibenzo-18-crown-6 polyether and dicyclohexyl-18-crown-6 polyether.
警示用语：
Danger
危险分类
Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Carc. 2 - Flam. Liq. 3
补充剂危害
储存分类代码
3 - Flammable liquids
WGK
WGK 2
闪点(°F)
131.0 °F - closed cup
闪点(°C)
55.0 °C - closed cup
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
非剧毒-急性毒性1
危险化学品
Thiodiglycolic acid: a major metabolite of bis(2-chloroethyl)ether.
R D Lingg et al.
Toxicology and applied pharmacology, 47(1), 23-34 (1979-01-01)
Macrocyclic Polyethers: Dibenzo-18-crown-6 Polyether and Dicyclohexyl-18-crown-6 Polyether.
Pedersen CJ.
Organic Syntheses, 66-66 (1972)
R D Lingg et al.
Archives of environmental contamination and toxicology, 11(2), 173-183 (1982-01-01)
Male rats were given single peroral doses of bis(1-14C-2-chloroethyl)ether ([1-14C]BCEE) (40 mg/kg) and of bis(1-14C-2-chloroisopropyl)ether ([1-14C]BCIE) (90 mg/kg). Excretion of 14CO2 and urinary 14C was followed for 48 hr. The time required to eliminate one half of the dose was
L M Gwinner et al.
Carcinogenesis, 4(11), 1483-1486 (1983-11-01)
The roles of chloroethylene oxide (CEO) and chloroacetaldehyde (CAA) in carcinogenicity of vinyl chloride (VC) have been studied by comparing biological effects of VC exposure with those of 2,2'-dichlorodiethylether (bis(chloroethyl)ether, BCEE) as a metabolic precursor of CAA. Biological end-points investigated
[Medical topics: bischloromethyl ether and lung cancer].
K Shibusawa
[Kango] Japanese journal of nursing, 37(14), 82-82 (1985-12-01)
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