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Merck
CN

35405

Supelco

α-Zearalanol solution

~10 μg/mL in acetonitrile, analytical standard

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别名:
(3S,7R)-3,4,5,6,7,8,9,10,11,12-Decahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one solution, 2,4-Dihydroxy-6-(6α,10-dihydroxyundecyl)benzoic acid μ-lactone solution
经验公式(希尔记法):
C18H26O5
CAS号:
分子量:
322.40
EC 号:
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:

等级

analytical standard

保质期

limited shelf life, expiry date on the label

药品控制

regulated under CDSA - not available from Sigma-Aldrich Canada

存货情况

not available in Canada

浓度

~10 μg/mL in acetonitrile

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

cleaning products
cosmetics
food and beverages
personal care

格式

single component solution

储存温度

−20°C

SMILES字符串

C[C@H]1CCC[C@H](O)CCCCCc2cc(O)cc(O)c2C(=O)O1

InChI

1S/C18H26O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,14,19-21H,2-9H2,1H3/t12-,14+/m0/s1

InChI key

DWTTZBARDOXEAM-GXTWGEPZSA-N

一般描述

α-Zearalanol is a resorcyclic acid lactone. It is a plant derived, nonsteroidal phytoestrogen, often used as a dietary supplement.

应用

α-Zearalanol may be used as an analytical reference standard for the determination of the analyte in traditional Chinese medicines, human and animal urine by various chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

分析说明

purity : ≥97.0% (HPLC)

象形图

FlameExclamation mark

警示用语:

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

WGK

WGK 2

闪点(°F)

35.6 °F

闪点(°C)

2.0 °C

法规信息

危险化学品
高风险级别生物产品--毒素类产品

分析证书(COA)

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A rapid method for simultaneous determination of zearalenone, α-zearalenol, β-zearalenol, zearalanone, α-zearalanol and β-zearalanol in traditional Chinese medicines by ultra-high-performance liquid chromatography-tandem mass spectrometry.
Han Z, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 879(5-6), 411-420 (2011)
Shaohui Zong et al.
Journal of bone and mineral metabolism, 30(2), 136-143 (2011-07-21)
To assess the ability of α-zearalanol (α-ZAL) to prevent bone loss in an ovariectomized (OVX) rat model of osteoporosis, α-ZAL was administered intragastrically to rats. After 35 days, the total body bone mineral density (BMD) was assessed in all rats. All
Marcella L Card et al.
Journal of agricultural and food chemistry, 60(6), 1480-1487 (2012-01-10)
Surface runoff from manure-fertilized fields is a significant source of endocrine-disrupting compounds (EDCs) in the environment. Sorption by soils may play a major role in the environmental fate of manure-borne EDCs, including 17α- and 17β-estradiol (17α-E2 and 17β-E2), estrone (E1)
Hongfeng Wang et al.
The Journal of reproduction and development, 58(3), 338-343 (2012-03-27)
Alpha-Zearalenol (α-ZEA) is one of derivatives from Zearalenone (ZEA) which impacts mammalian reproduction and development. Previous studies have shown that pigs are sensitive to the estradiol-like effects of α-ZEA. However, the effect of α-ZEA for the early embryonic development has
Hui Zhou et al.
Nature chemical biology, 8(4), 331-333 (2012-03-13)
Iterative highly reducing polyketide synthases from filamentous fungi are the most complex and enigmatic type of polyketide synthase discovered to date. Here we uncover an unusual degree of programming by the hypothemycin highly reducing polyketide synthase, in which a single

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