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Merck
CN

34392

Supelco

甲基二溴戊二腈

analytical standard

别名:

1,2-二溴-2,4-二氰丁烷, 1-溴-1-(溴甲基)-1,3-丙烷二甲腈, 2-溴-2-(溴甲基)戊二腈

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About This Item

经验公式(希尔记法):
C6H6Br2N2
CAS号:
分子量:
265.93
EC 号:
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

51-55 °C

应用

environmental

包装形式

neat

储存温度

2-8°C

SMILES字符串

BrCC(Br)(CCC#N)C#N

InChI

1S/C6H6Br2N2/c7-4-6(8,5-10)2-1-3-9/h1-2,4H2

InChI key

DHVLDKHFGIVEIP-UHFFFAOYSA-N

一般描述

Methyldibromoglutaronitrile (MDBGN) is a bromine-containing preservative and a clinically significant allergen as investigated from animal/human clinical studies.
Methyldibromoglutaronitrile can be generally used as a preservative in the cosmetic industry for many skin care products.

应用

Methyldibromoglutaronitrile may be used as an analytical reference standard for the quantification of the analyte in cosmetic products using ultra performance liquid chromatography (UPLC) coupled to inductively coupled plasma mass spectrometry (ICP-MS) and gas chromatography followed by mass spectrometry technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

推荐产品

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象形图

CorrosionExclamation mark

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Skin Corr. 1B

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

农药列管产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Determination of methyldibromoglutaronitrile in cosmetic products by high-performance liquid chromatography with electrochemical detection: Method validation
Rastogi CS, et al.
Journal of Chromatography A, 1031(1-2), 315-317 (2004)
Patch testing with methyldibromoglutaronitrile
Geier J, et al.
American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society, 11, 207-212 (2000)
Charlotte Gotthard Mortz et al.
Current opinion in allergy and clinical immunology, 8(5), 428-432 (2008-09-05)
To give selected new information on contact allergy and allergic contact dermatitis with focus on diagnostic procedures and pitfalls. Recent studies dealing with common contact allergens have improved our understanding of the relationship between positive patch tests and the clinical
Jakob Torp Madsen et al.
Contact dermatitis, 63(4), 209-214 (2010-08-25)
Ethosomes and liposomes are ultra-small vesicles capable of encapsulating drugs and cosmetic ingredients for topical use, thereby potentially increasing bioavailability and clinical efficacy. So far, few reports have suggested that formulation of cosmetic ingredients in vesicular carrier systems may increase
Louise Arup Fischer et al.
Contact dermatitis, 61(4), 201-208 (2009-10-15)
Allergic contact dermatitis is common and can be prevented. The relationship between thresholds for patch tests and the repeated open application test (ROAT) is unclear. It would be desirable if patch test and ROAT data from already sensitized individuals could

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