所有图片(2)
About This Item
经验公式（希尔记法）:
C16H15FN2O4
CAS号:
分子量:
318.30
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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等级
analytical standard
质量水平
产品线
VETRANAL®
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
clinical testing
包装形式
neat
储存温度
2-8°C
SMILES字符串
C[C@H]1COc2c3N1C=C(C(O)=O)C(=O)c3cc(F)c2C4(N)CC4
InChI
1S/C16H15FN2O4/c1-7-6-23-14-11(16(18)2-3-16)10(17)4-8-12(14)19(7)5-9(13(8)20)15(21)22/h4-5,7H,2-3,6,18H2,1H3,(H,21,22)/t7-/m0/s1
InChI key
XAGMUUZPGZWTRP-ZETCQYMHSA-N
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一般描述
Chemical structure: quinolone
Pazufloxacin is a fluoroquinolone antibiotic, which shows broad spectrum activity in anti-infective chemotherapy.
应用
Pazufloxacin may be used as a reference standard in the determination of pazufloxacin in serum and plasma samples using high performance liquid chromatography coupled with fluorescence detector (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
法律信息
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
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Warning
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Shinzaburo Minami et al.
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 122(2), 161-178 (2003-08-02)
Pazufloxacin mesilate (PZFX: Pasil INJECTION, Pazucross INJECTION) is a novel injectable quinolone antibiotic that was discovered by Toyama Chemical Co., Ltd. and codeveloped by Toyama Chemical Co. Ltd. and Mitsubishi Pharma Corporation. Laboratory studies indicated that PZFX reached high plasma
Naoyuki Miyashita et al.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 26(5), 411-417 (2020-02-23)
Legionella species are consistently identified as some of the most common causative agents of severe community-acquired pneumonia (CAP) or nosocomial pneumonia. Although the number of reported Legionella infection cases is gradually increasing in Japan, most cases are diagnosed by a
A P Johnson
Current opinion in investigational drugs (London, England : 2000), 1(1), 52-57 (2001-03-16)
Toyama Chemical Co Ltd is developing pazufloxacin (T-3761), an orally active synthetic quinolone antibiotic, which is awaiting registration following successful clinical trials that demonstrated its pharmacological similarities to tosufloxacin (Toyama Chemical Co) with respect to clinical efficacy, adverse effects and
Simultaneous measurement of pazufloxacin, ciprofloxacin, and levofloxacin in human serum by high-performance liquid chromatography with fluorescence detection.
Watabe S, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 878(19), 1555-1561 (2010)
First liquid chromatography method for the simultaneous determination of levofloxacin, pazufloxacin, gatifloxacin, moxifloxacin and trovafloxacin in human plasma.
Sousa J, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 930, 104-111 (2013)
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