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Merck
CN

34130

镰刀菌烯酮-X 溶液

100 μg/mL in acetonitrile, analytical standard

别名:

3α,7α,15-Trihydroxy-4β-acetoxy-12,13-epoxytrichothec-9-en-8-one, FusX

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关于此项目

经验公式（希尔记法）:
C17H22O8
化学文摘社编号:
23255-69-8
分子量:
354.35
NACRES:
NA.24
PubChem Substance ID:
329754836
UNSPSC Code:
41116107
EC Number:
200-835-2
MDL number:
MFCD00078778

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InChI

1S/C17H22O8/c1-7-4-9-16(5-18,12(22)10(7)20)15(3)13(24-8(2)19)11(21)14(25-9)17(15)6-23-17/h4,9,11-14,18,21-22H,5-6H2,1-3H3/t9-,11-,12-,13-,14-,15-,16-,17+/m1/s1

InChI key

XGCUCFKWVIWWNW-CAYGJDLQSA-N

SMILES string

CC(=O)O[C@@H]1[C@@H](O)[C@H]2O[C@@H]3C=C(C)C(=O)[C@@H](O)[C@]3(CO)[C@]1(C)[C@]24CO4

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

concentration

100 μg/mL in acetonitrile

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

Quality Level

100

相关类别

General description

Certan Vial
Fusarenon X, is a trichothecene mycotoxin, which is produced by Fusarium nivale fungi, naturally occurring in crops such as wheat and barley.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCP3940
BCCP0650
BCCL3591
BCCK3026
BCCG5947

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Low tumor incidence in rats with long-term feeding of fusarenon-X, a cytotoxic trichothecene produced by Fusarium nivale
Saito M, et al.
The Japanese Journal of Experimental Medicine, 50, 293-302 (1980)
The fates of trichothecene mycotoxins, nivalenol and fusarenon-X, in mice
Poapolathep A, et al.
Toxicon, 41, 1047-1054 (2003)
Fusarenon-X induced apoptosis in HL-60 cells depends on caspase activation and cytochrome c release
Miura K, et al.
Toxicology, 172, 103-112 (2002)
K Miura et al.
Toxicology, 127(1-3), 195-206 (1998-08-12)
The effects of fusarenon-X (12,13-epoxytrichothecene; FX) on mouse thymus and T-cell subpopulations were studied. In mice that received three intraperitoneal injections of FX, the thymus showed severe atrophy, the thymic cortex almost completely disappeared, and the total number of thymocytes
J Li et al.
The Journal of veterinary medical science, 59(3), 191-199 (1997-03-01)
Male 5-week-old Wistar rats orally (po) administered with fusarenon-X (FX) 1.5 mg/kg and control rats po-treated with distilled water were sacrificed at 0-48 hr after gavage. FX-administered rats showed significant dilatation of the stomach with increased fluid contents at 1-24
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