34093
克罗散泰
PESTANAL®, analytical standard
别名:
N-[5-氯-4-(4-氯-α-氰基苄基)-2-甲基苯基]-2-羟基-3,5-二碘苯甲酰胺, 氯氰碘柳胺
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关于此项目
经验公式（希尔记法）:
C22H14Cl2I2N2O2
化学文摘社编号:
分子量:
663.07
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
260-967-1
MDL number:
InChI key
JMPFSEBWVLAJKM-UHFFFAOYSA-N
InChI
1S/C22H14Cl2I2N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30)
SMILES string
Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c3cc(I)cc(I)c3O
grade
analytical standard
product line
PESTANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
agriculture
environmental
format
neat
storage temp.
2-8°C
Quality Level
General description
Closantel belongs to the salicylanilide class of anthelmintics, that can extensively bind to the plasma albumin. It can be effectively used against, a vast range of blood feeding internal parasites.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Chronic 4
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
K M Cooper et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 29(8), 1263-1271 (2012-05-29)
The ProSafeBeef project studied the prevalence of residues of anthelmintic drugs used to control parasitic worms and fluke in beef cattle in Ireland. Injured (casualty) cattle may enter the human food chain under certain conditions, verified by an attending veterinarian
Haemonchus contortus: the uptake and metabolism of closantel
Rothwell J and Sangster N
International Journal For Parasitology, 27, 313-319 (1997)
L Cromie et al.
Journal of veterinary pharmacology and therapeutics, 29(3), 205-211 (2006-05-04)
Two studies are described on the pharmacokinetics of a combination anthelmintic consisting of ivermectin and closantel for use in cattle. In the first, the pharmacokinetics of both active drugs in the combination were compared with the formulation with either ivermectin
R E B Hanna et al.
Veterinary parasitology, 142(1-2), 78-90 (2006-08-12)
Sixteen calves approximately 6 months old were each infected with 500 metacercariae of Fasciola hepatica. Thirty-two days later they were weighed and divided into two groups, and on day 35 all calves in one of the groups were injected subcutaneously
The effect of a parenteral ivermectin/closantel injection on the growth and reproductive development of early immature Fasciola hepatica in cattle
Hanna.B.E.R, et al.
Veterinary Parasitology, 142, 78-90 (2006)
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