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Merck
CN

34091

氟苯达唑

VETRANAL®, analytical standard

别名:

[5-(4-氟苯甲酰)-1H-苯并咪唑-2-基]氨基甲酸甲酯, 氟苯咪唑

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关于此项目

经验公式(希尔记法):
C16H12FN3O3
化学文摘社编号:
分子量:
313.28
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
250-624-4
MDL number:
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产品名称

氟苯达唑, VETRANAL®, analytical standard

Quality Level

InChI

1S/C16H12FN3O3/c1-23-16(22)20-15-18-12-7-4-10(8-13(12)19-15)14(21)9-2-5-11(17)6-3-9/h2-8H,1H3,(H2,18,19,20,22)

InChI key

CPEUVMUXAHMANV-UHFFFAOYSA-N

SMILES string

COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccc(F)cc3

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
VETRANAL® analytical standard can be used in the liquid chromatography coupled to mass spectrometry (LC-MS/MS) procedure, performed for the analysis of macrocyclic lactones in milk.

General description

Flubendazol is a broad spectrum anthelmintic, which belongs to the class of compounds known as benzimidazoles. It can be widely used in veterinary and human medicine. It mainly finds applications in deworming poultry, swine, dogs and cats.
Flubendazol is an injectable benzimidazole drug; though it is poorly absorbed it is quite effective in the treatment of trycocephalus, ascaris and oxyuriasis in both children and adults.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

wgk

WGK 2

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jung-Min Lee et al.
The Korean journal of parasitology, 49(3), 273-275 (2011-11-11)
Praziquantel is the drug of choice for clonorchiasis. Since clonorchiasis is endemic in most river basins, praziquantel has been widely used for 30 years in Korea. A 54-year-old Korean woman suffered from hypersensitive reactions, such as nausea, dyspnea, rash, and
S Squires et al.
Veterinary parasitology, 185(2-4), 352-354 (2011-10-26)
The efficacy of a commercially available flubendazole-based product and a commercially available herbal product were compared against three species of helminth parasites of chickens: Ascaridia galli, Heterakis gallinarum and Capillaria spp. A total of 48 naturally infected chickens were used
V Vandenberge et al.
Poultry science, 91(5), 1248-1255 (2012-04-14)
Chemical residues may be present in eggs from laying hens' exposure to drugs or contaminants. These residues may pose risks to human health. In this study, laying hens received experimental feed containing flubendazole or tylosin at cross contamination levels of
Residues of Some Veterinary Drugs in Animals and Foods (1993)
Integrated pharmacological assessment of flubendazole potential for use in sheep: disposition kinetics, liver metabolism and parasite diffusion ability
Moreno.L, et al.
Journal of Veterinary Pharmacology and Therapeutics, 27, 299-308 (2004)

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