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About This Item
经验公式（希尔记法）:
C8H8Cl3N3O4S2
CAS号:
分子量:
380.66
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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等级
analytical standard
质量水平
产品线
VETRANAL®
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
包装形式
neat
SMILES字符串
Nc1cc(\C(Cl)=C(\Cl)Cl)c(cc1S(N)(=O)=O)S(N)(=O)=O
InChI
1S/C8H8Cl3N3O4S2/c9-7(8(10)11)3-1-4(12)6(20(14,17)18)2-5(3)19(13,15)16/h1-2H,12H2,(H2,13,15,16)(H2,14,17,18)
InChI key
QOVTVIYTBRHADL-UHFFFAOYSA-N
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一般描述
Clorsulon, is a benzene sulphonamide and a flukicide, which is found to be effective against the adult and immature form of liver fluke, Fasciola hepatica in cattle.
应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
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法律信息
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
Eyeshields, Gloves, type N95 (US)
Y Vera Montenegro et al.
Parasitology research, 91(1), 1-4 (2003-07-05)
The efficacy of 5-chloro-2-methylthio-6-(1-napthyloxy)-1H-benzimidazole was evaluated with three commercial fasciolicides in terms of the percentage of egg reduction in cattle. Fifty Swiss cows were selected for inclusion in the trial based on finding eggs of Fasciola hepatica in their feces.
S F Sundlof et al.
Journal of veterinary pharmacology and therapeutics, 15(3), 282-291 (1992-09-01)
Clorsulon was measured in plasma and urine of sheep and goats after administration of a single intravenous (i.v.) and after a single oral dose of 7 mg/kg. A three-compartment model with elimination occurring from the central compartment was determined to
Induction of reversible urothelial cell hyperplasia in rats by clorsulon, a flukicide with weak carbonic anhydrase inhibitory activity
Lankas.RG and Peter.PC
Food And Chemical Toxicology, 30, 297-306 (1992)
M Meaney et al.
Parasitology research, 95(3), 201-212 (2005-01-13)
Three experiments have been carried out in vitro to determine the effect of oral and trans-tegumental uptake of clorsulon on the fine structure of the tegument and gut of Fasciola hepatica. Changes were assessed by transmission electron microscopy. In the
M Meaney et al.
Parasitology research, 92(3), 232-241 (2004-01-10)
Using transmission electron microscopy (TEM), both the tegument and gut of Fasciola hepatica were examined in an effort to identify and characterise the ultrastructural changes induced following treatment with the flukicidal drug clorsulon. Male Sprague-Dawley rats infected with F. hepatica
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