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等级
ACS reagent
puriss. p.a.
蒸汽密度
<1 (vs air)
蒸汽压
1 mmHg ( 51 °C)
检测方案
≥99.5%
杂质
≤0.002% heavy metals (as Pb)
≤0.005% water insolubles
灼烧残渣
≤0.01% (as SO4)
折射率
n20/D 1.62 (lit.)
bp
196 °C (lit.)
mp
54-58 °C (lit.)
密度
1.62 g/mL at 25 °C (lit.)
痕量阴离子
chloride (Cl-): ≤10 mg/kg
nitrate (NO3-): ≤20 mg/kg
phosphate (PO43-): ≤5 mg/kg
sulfate (SO42-): ≤100 mg/kg
痕量阳离子
Cu: ≤5 mg/kg
Fe: ≤10 mg/kg
适用性
complies for appearance of solution
SMILES字符串
OC(=O)C(Cl)(Cl)Cl
InChI
1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)
InChI key
YNJBWRMUSHSURL-UHFFFAOYSA-N
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一般描述
Trichloroacetic acid (TCA) is a chlorinated acetic acid. It is one of the major metabolite of trichloroethylene (TCE).
应用
Trichloroacetic acid may be used for the quantification of inorganic phosphorus in various biological samples (serum, urine and stool ash solutions). It may be used for the elimination of acid-soluble and lipid phosphorous during the quantitative estimation of deoxyribonucleic acid, ribonucleic acid and phosphoproteins in animal tissues. 10% trichloroacetic acid may be employed for the preparation of radioactive proteins.
传统上用于沉淀蛋白质。用于通过定量沉淀测定蛋白质浓度。用作脱钙剂和显微镜样品的固定剂。
警示用语：
Danger
危险声明
危险分类
Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A
WGK
WGK 2
闪点(°F)
closed cup
闪点(°C)
closed cup
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
Solubility of albumin in alcohol after precipitation by trichloroacetic acid: a simplified procedure for separation of albumin.
J R DEBRO et al.
Nature, 178(4541), 1067-1067 (1956-11-10)
A method for the determination of desoxyribonucleic acid, ribonucleic acid, and phosphoproteins in animal tissues.
G SCHMIDT et al.
The Journal of biological chemistry, 161, 83-89 (1945-01-01)
A microcolorimetric method for the determination of inorganic phosphorus.
H H TAUSSKY et al.
The Journal of biological chemistry, 202(2), 675-685 (1953-06-01)
S L Herren-Freund et al.
Toxicology and applied pharmacology, 90(2), 183-189 (1987-09-15)
Trichloroethylene (TCE) has previously been shown to be carcinogenic in mouse liver when administered by daily gavage in corn oil. The metabolism of TCE results, in part, in the formation of trichloroacetic acid (TCA) as a major metabolite and dichloroacetic
Valentina Folgiero et al.
Oncotarget, 5(8), 2052-2064 (2014-06-07)
Microenvironmental factors contribute to the immune dysfunction characterizing acute myeloid leukemia (AML). Indoleamine 2,3-dioxygenase 1 (IDO1) is an interferon (IFN)-γ-inducible enzyme that degrades tryptophan into kynurenine, which, in turn, inhibits effector T cells and promotes regulatory T-cell (Treg) differentiation. It
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