所有图片(1)
About This Item
经验公式（希尔记法）:
C19H22FN3O3
CAS号:
分子量:
359.39
Beilstein:
5307824
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
analytical standard
质量水平
Agency
EPA 1694
产品线
VETRANAL®
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
应用
clinical testing
格式
neat
作用机制
DNA synthesis | interferes
enzyme | inhibits
SMILES字符串
CCN1CCN(CC1)c2cc3N(C=C(C(O)=O)C(=O)c3cc2F)C4CC4
InChI
1S/C19H22FN3O3/c1-2-21-5-7-22(8-6-21)17-10-16-13(9-15(17)20)18(24)14(19(25)26)11-23(16)12-3-4-12/h9-12H,2-8H2,1H3,(H,25,26)
InChI key
SPFYMRJSYKOXGV-UHFFFAOYSA-N
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一般描述
化学结构式：氟喹诺酮类
恩诺沙星是一种广谱氟喹诺酮类抗生素，广泛用于人药和兽药。该药通过抑制细菌 DNA 促旋酶和 DNA 拓扑异构酶 IV (Topo IV) 发挥作用，这两种酶是负责 DNA 复制的重要酶。
应用
恩诺沙星可用作分析参考标准品，用于通过各种分析技术测定牛奶、 猪血浆、 山羊奶和食品样品中的分析物。
有关合适仪器技术的更多信息，请参考产品的分析证书。如需进一步支持，请联系技术服务部门。
法律信息
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险声明
危险分类
Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1
WGK
WGK 3
个人防护装备
Eyeshields, Gloves, type N95 (US)
Determination of residual enrofloxacin in food samples by a sensitive method of chemiluminescence enzyme immunoassay
Yu F, et al.
Food Chemistry, 149, 71-75 (2014)
Determination of enrofloxacin and its metabolite ciprofloxacin in goat milk by high-performance liquid chromatography with diode-array detection: Optimization and validation
Cinquina AL, et al.
Journal of Chromatography A, 987(1-2), 221-226 (2003)
Simple, rapid determination of enrofloxacin and ciprofloxacin in bovine milk and plasma by high-performance liquid chromatography with fluorescence detection
Idowu OR and Peggins JO
Journal of Pharmaceutical and Biomedical Analysis, 35(1), 143-153 (2004)
Determination of ciprofloxacin, enrofloxacin and flumequine in pig plasma samples by capillary isotachophoresis-capillary zone electrophoresis
Hernandez M, et al.
Journal of Chromatography. B, Biomedical Applications, 772(1), 163-172 (2002)
Kristine H Wammer et al.
Water research, 47(1), 439-448 (2012-11-13)
Fluoroquinolone (FQ) antibacterial compounds are frequently detected in the aquatic environment, and photodegradation is expected to play an important role in FQ fate in some sunlit surface waters. This study investigated the direct aquatic photochemistry of three FQs: norfloxacin, ofloxacin
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