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Merck
CN

33490

Supelco

HMDI

analytical standard

别名:

4,4′-二异氰酸酯二环己基甲烷, 1,1'-亚甲二(4-异氰酸基环己烷), 4,4′-HMDI, 二环己基甲烷-4,4'-二异氰酸酯

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About This Item

线性分子式:
CH2(C6H10NCO)2
CAS号:
分子量:
262.35
Beilstein:
2217800
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

质量

mixture of isomers

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

environmental

格式

neat

SMILES字符串

O=C=NC1CCC(CC1)CC2CCC(CC2)N=C=O

InChI

1S/C15H22N2O2/c18-10-16-14-5-1-12(2-6-14)9-13-3-7-15(8-4-13)17-11-19/h12-15H,1-9H2

InChI key

KORSJDCBLAPZEQ-UHFFFAOYSA-N

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一般描述

该物质被列入欧盟法规10/2011中关于拟与食品接触的塑料的积极清单。

应用

有关合适仪器技术的更多信息,请参考产品分析证书。如需进一步支持,请联系技术服务部门。

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 2 Inhalation - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

闪点(°F)

235.4 °F - closed cup

闪点(°C)

113 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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分析证书(COA)

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Sanjay Gandhi et al.
American journal of obstetrics and gynecology, 192(5), 1643-1648 (2005-05-20)
The purpose of this study was to examine the histopathologic changes of HMDI (Hexamethylene di-isocyanate) cross-linked porcine dermis grafts used for suburethral sling surgery. Twelve patients underwent reoperation with graft removal for urinary retention or recurrent stress urinary incontinence after
Selvaraj Nagarajan et al.
Journal of biomedical materials research. Part A, 99(3), 410-417 (2011-10-25)
Urethane polymers (PU) have been prepared from low-molecular weight polylactic acid (PLA) and hexamethylene diisocyanate (HMDI) using polydimethylsiloxane (PDMS) as a chain extender. These formed the supporting polymeric matrix of curcumin-containing PU membranes which were prepared using a solvent evaporation
Jeff C H Donovan et al.
Dermatitis : contact, atopic, occupational, drug, 20(4), 214-217 (2009-10-07)
Isocyanates are widely used in the manufacturing of rigid and flexible foams, fibers, and coatings such as paints, varnishes, and elastomers but are rarely reported as contact sensitizers. The aliphatic diisocyanate dicyclohexylmethane-4,4'-diisocyanate (DMDI) is known to be a strong cutaneous
J C Stadler et al.
Toxicology and applied pharmacology, 78(3), 445-450 (1985-05-01)
Groups of English smooth-haired guinea pigs and BALB/cBy mice were exposed to dicyclohexylmethane-4,4'-diisocyanate (HMDI) and picryl chloride (PiCl) by topical exposure. Guinea pigs were challenged 7 days later by patch testing and responses graded at 24 hr. Application of high
J Stadler et al.
Toxicology and applied pharmacology, 74(2), 244-249 (1984-06-30)
Exposure of workers to low-molecular-weight chemicals has been associated with delayed-onset hypersensitivity reactions in both the skin and the respiratory tract. The use of two animal models to examine factors affecting the production of delayed hypersensitivity to dicyclohexylmethane-4,4'-diisocyanate (HMDI) is

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