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经验公式(希尔记法):
C13H10BrCl2O2PS
化学文摘社编号:
分子量:
412.07
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
244-472-8
Beilstein/REAXYS Number:
2152663
MDL number:
InChI key
CVRALZAYCYJELZ-UHFFFAOYSA-N
InChI
1S/C13H10BrCl2O2PS/c1-17-19(20,9-5-3-2-4-6-9)18-13-8-11(15)10(14)7-12(13)16/h2-8H,1H3
SMILES string
COP(=S)(Oc1cc(Cl)c(Br)cc1Cl)c2ccccc2
grade
analytical standard
product line
PESTANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, NMR: suitable, gas chromatography (GC): suitable
mp
71-73 °C
suitability
passes test for identity (NMR)
application(s)
agriculture
environmental
format
neat
storage temp.
2-8°C
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相关类别
General description
Leptophos, an organophosphorus insecticide found to be persistent in the environment, shows neurotoxic effects in humans. Its mode of action for pest control involves the inhibition of acetylcholinesterase enzyme activity.
Application
Leptophos may be used as an analytical reference standard for the quantification of the analyte in vegetables using solid phase micro-extraction coupled with gas chromatography-flame photometric detector (SPME-GC-FPD).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - STOT SE 1
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
flash_point_f
>212.0 °F
flash_point_c
> 100 °C
法规信息
危险化学品
农药列管产品
此项目有
Photodegradation of leptophos.
Riskallah RM, et al.
Bulletin of Environmental Contamination and Toxicology, 23(1), 636-641 (1979)
Determination of organophosphorus pesticide residues in vegetables using solid phase micro-extraction coupled with gas chromatography-flame photometric detector.
Sapahin AH, et al.
Arabian Journal of Chemistry, 23(1), 636-641 (2014)
F Y Piao et al.
The Journal of toxicological sciences, 20(5), 609-617 (1995-11-01)
Delayed neurotoxicity induced by leptophos, an organophosphorus insecticide, was intensified in hens when phenylmethylsulfonyl fluoride (PMSF) at dose of 30, 60, and 120 mg/kg body weight was administered at different time intervals (24 hr, 3 days, and 5 days) for
M Farage-Elawar et al.
Journal of toxicology and environmental health, 23(2), 217-228 (1988-01-01)
The effects of multiple doses of desbromoleptophos, fenitrothion, and pure fenthion on brain acetylcholinesterase (AChE), brain neurotoxic esterase (NTE), and walking were investigated in immature chicks, below the age of sensitivity to organophosphorus ester-induced delayed neurotoxicity (OPIDN). Ten milligrams per
F Y Piao et al.
The Journal of toxicological sciences, 22(2), 99-109 (1997-05-01)
To estimate the delayed neurotoxic effect of OPs on the next generation, we tried two examinations; one was on the distribution of leptophos in tissues and eggs of hens which are highly susceptible to the delayed neurotoxic effect of OPs
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