Agency
USP/NF
reag. Ph. Eur.
质量水平
等级
puriss. p.a.
检测方案
99.7-101% (calc. to the dried substance)
形式
crystalline powder
技术
IR spectroscopy: suitable
杂质
≤0.001% heavy metals (as Pb)
≤0.02% ammonium (NH4)
≤0.1% water (Karl Fischer)
≤1.0% ninhydrin-positive substances
灼烧残渣
≤0.05% (as SO4)
缺失
≤0.5% loss on drying, 105°C, 2 h
pH值（酸碱度）
5.9-6.4 (20 °C, 5%)
pKa (25 °C)
(1) 2.35, (2) 9.60
2.35
mp
240 °C (dec.) (lit.)
痕量阴离子
chloride (Cl-): ≤30 mg/kg
sulfate (SO42-): ≤20 mg/kg
痕量阳离子
Fe: ≤5 mg/kg
适用性
in accordance for identity (IR)
SMILES字符串
NCC(O)=O
InChI
1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChI key
DHMQDGOQFOQNFH-UHFFFAOYSA-N
基因信息
rat ... Grin2a(24409)
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应用
甘氨酸可用作：
- 一种反应物，在天然土壤粘土催化的情况下与焦棓酸发生裂解和聚合反应。
- 一种催化剂，在芳基醛与丙二腈之间发生Knoevenagel反应C=C键。
- 一种试剂，用于芳基亚砜类和磺胺通过迁移重排实现联芳基无金属合成。
生化/生理作用
脊髓中的抑制性神经递质，NMDA受体的变构调节器。
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Alexander Carvajal-González et al.
Brain : a journal of neurology, 137(Pt 8), 2178-2192 (2014-06-22)
The clinical associations of glycine receptor antibodies have not yet been described fully. We identified prospectively 52 antibody-positive patients and collated their clinical features, investigations and immunotherapy responses. Serum glycine receptor antibody endpoint titres ranged from 1:20 to 1:60 000.
Richard A Felix et al.
Brain structure & function, 220(5), 2639-2652 (2014-06-30)
The mammalian superior paraolivary nucleus (SPON) is a major source of GABAergic inhibition to neurons in the inferior colliculus (IC), a well-studied midbrain nucleus that is the site of convergence and integration for the majority ascending auditory pathways en route
Zoé Husson et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(28), 9418-9431 (2014-07-11)
The principal neurons of the cerebellar nuclei (CN), the sole output of the olivo-cerebellar system, receive a massive inhibitory input from Purkinje cells (PCs) of the cerebellar cortex. Morphological evidence suggests that CN principal cells are also contacted by inhibitory
Li-Chun Tu et al.
The EMBO journal, 32(24), 3220-3230 (2013-11-12)
Nuclear pore complexes (NPCs) mediate cargo traffic between the nucleus and the cytoplasm of eukaryotic cells. Nuclear transport receptors (NTRs) carry cargos through NPCs by transiently binding to phenylalanine-glycine (FG) repeats on intrinsically disordered polypeptides decorating the NPCs. Major impediments
Suzanne L Grant et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 844(2), 278-282 (2006-08-08)
A simple and versatile methodology using high-performance liquid chromatography (HPLC) with fluorimetric detection was developed to simultaneously determine d-serine along with other metabolically related neuroactive amino acids in the glutamatergic system: L-serine, L-glutamate, L-glutamine, and glycine. On-column sensitivity was in
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