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Merck
CN
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文件

32830

Sigma-Aldrich

L-2,4-二氨基丁酸 二盐酸盐

≥95.0%

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别名:
(2S)-2,4-Diaminobutanoic acid dihydrochloride, L-2,4-Diaminobutanoic acid dihydrochloride
线性分子式:
NH2CH2CH2CH(NH2)COOH · 2HCl
CAS号:
1883-09-6
分子量:
191.06
Beilstein:
5763078
EC 号:
217-542-0
MDL编号:
MFCD00064561
UNSPSC代码:
12352106
PubChem化学物质编号:
329754346
NACRES:
NA.22

质量水平

100

检测方案

≥95.0% (AT)
≥95.0%

旋光性

[α]20/D +14.5±1.5°, c = 3.67% in H2O

反应适用性

reaction type: solution phase peptide synthesis

mp

197-200 °C (dec.)

溶解性

water: soluble 0.5 g/10 mL

应用

peptide synthesis

SMILES字符串

Cl.Cl.NCC[C@H](N)C(O)=O

InChI

1S/C4H10N2O2.2ClH/c5-2-1-3(6)4(7)8;;/h3H,1-2,5-6H2,(H,7,8);2*1H/t3-;;/m0../s1

InChI key

CKAAWCHIBBNLOJ-QTNFYWBSSA-N

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相关类别

一般描述

L-2,4-二氨基丁酸二盐酸盐是非天然氨基酸衍生物。

应用

L-2,4-二氨基丁酸二盐酸盐可用于通过 HPLC-FD、UHPLC-UV、UHPLC-MS 和三重四极杆串联质谱法（UHPLC-MS/MS）从二氨基酸中区分出 β-N-甲基氨基-L-丙氨酸。它适用于定量海鲜中神经毒素 β-N-甲基氨基-L-丙氨酸（BMAA）。它可用作氨基酸分析的内标

注意

可能会释放出 HCl

象形图

CorrosionExclamation mark
GHS05,GHS07

警示用语：

Danger

危险声明

H315,H318,H335

危险分类

Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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Liying Jiang et al.
Scientific reports, 4, 6931-6931 (2014-11-07)
The neurotoxin β-N-methylamino-L-alanine (BMAA) produced naturally by cyanobacteria, diatoms and dinoflagellates can be transferred and accumulated up the food chain, and may be a risk factor for neurodegenerative diseases. This study provides the first systematic screening of BMAA exposure of
Sun-Jung Kim et al.
International journal of systematic and evolutionary microbiology, 61(Pt 1), 155-159 (2010-02-23)
A Gram-positive, non-motile bacterium, designated KSL51201-037(T), was isolated from Anyang stream, Republic of Korea, and was characterized using a polyphasic taxonomic approach. Comparative 16S rRNA gene sequence analysis showed that strain KSL51201-037(T) belonged to the family Microbacteriaceae of the class
G S N Reddy et al.
International journal of systematic and evolutionary microbiology, 58(Pt 9), 2229-2234 (2008-09-05)
Strain PON10(T) is a yellow-pigmented, Gram-positive, aerobic, motile, rod-shaped bacterium isolated from the Pindari glacier of the Indian Himalayas. The cell-wall peptidoglycan contained DL-diaminobutyric acid as the diamino acid. The predominant fatty acids were anteiso-C(15:0), anteiso-C(17:0) and iso-C(16:0) and the
C Müller et al.
Antimicrobial agents and chemotherapy, 51(3), 1028-1037 (2007-01-16)
Actinoplanes friuliensis produces the lipopeptide antibiotic friulimicin, which is a cyclic peptide with one exocyclic amino acid linked to a branched-chain fatty acid acyl residue. The structural relationship to daptomycin and the excellent antibacterial performance of friulimicin make the antibiotic
Sherry M Tsai et al.
Nucleic acids research, 35(1), 307-316 (2006-12-16)
Hairpin polyamide-chlorambucil conjugates containing an alpha-diaminobutyric acid (alpha-DABA) turn moiety are compared to their constitutional isomers containing the well-characterized gamma-DABA turn. Although the DNA-binding properties of unconjugated polyamides are similar, the alpha-DABA conjugates display increased alkylation specificity and decreased rate
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