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Merck
CN

32830

Sigma-Aldrich

L-2,4-二氨基丁酸 二盐酸盐

≥95.0%

别名:

(2S)-2,4-Diaminobutanoic acid dihydrochloride, L-2,4-Diaminobutanoic acid dihydrochloride

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About This Item

线性分子式:
NH2CH2CH2CH(NH2)COOH · 2HCl
CAS号:
分子量:
191.06
Beilstein:
5763078
EC 号:
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

≥95.0% (AT)
≥95.0%

旋光性

[α]20/D +14.5±1.5°, c = 3.67% in H2O

反应适用性

reaction type: solution phase peptide synthesis

mp

197-200 °C (dec.)

溶解性

water: soluble 0.5 g/10 mL

应用

peptide synthesis

SMILES字符串

Cl.Cl.NCC[C@H](N)C(O)=O

InChI

1S/C4H10N2O2.2ClH/c5-2-1-3(6)4(7)8;;/h3H,1-2,5-6H2,(H,7,8);2*1H/t3-;;/m0../s1

InChI key

CKAAWCHIBBNLOJ-QTNFYWBSSA-N

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一般描述

L-2,4-二氨基丁酸二盐酸盐是非天然氨基酸衍生物。

应用

L-2,4-二氨基丁酸二盐酸盐可用于通过 HPLC-FD、UHPLC-UV、UHPLC-MS 和三重四极杆串联质谱法(UHPLC-MS/MS)从二氨基酸中区分出 β-N-甲基氨基-L-丙氨酸。它适用于定量海鲜中神经毒素 β-N-甲基氨基-L-丙氨酸(BMAA)。它可用作氨基酸分析的内标

注意

可能会释放出 HCl

象形图

CorrosionExclamation mark

警示用语:

Danger

危险声明

危险分类

Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The neurotoxin β-N-methylamino-L-alanine (BMAA) produced naturally by cyanobacteria, diatoms and dinoflagellates can be transferred and accumulated up the food chain, and may be a risk factor for neurodegenerative diseases. This study provides the first systematic screening of BMAA exposure of
Internal standards for amino acid analysis.
J F Riordan et al.
Methods in enzymology, 47, 31-40 (1977-01-01)
Derek Craighead et al.
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 10 Suppl 2, 96-100 (2009-12-16)
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Qing Li et al.
Organic letters, 12(5), 1080-1083 (2010-02-11)
The first highly diastereo- and enantioselective catalytic asymmetric Michael addition of glycine derivatives to nitroalkenes have been developed. The enantioselectivity of ortho-substituted products can be significantly improved by using a new 1,2-P,N-ferrocene ligand L5. The alpha,gamma-diaminoacid derivative was obtained without
Sun-Jung Kim et al.
International journal of systematic and evolutionary microbiology, 61(Pt 1), 155-159 (2010-02-23)
A Gram-positive, non-motile bacterium, designated KSL51201-037(T), was isolated from Anyang stream, Republic of Korea, and was characterized using a polyphasic taxonomic approach. Comparative 16S rRNA gene sequence analysis showed that strain KSL51201-037(T) belonged to the family Microbacteriaceae of the class

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