推荐产品
等级
analytical standard
质量水平
产品线
VETRANAL®
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
格式
neat
SMILES字符串
OC(CCCN1CCN(CC1)c2ccccn2)c3ccc(F)cc3
InChI
1S/C19H24FN3O/c20-17-8-6-16(7-9-17)18(24)4-3-11-22-12-14-23(15-13-22)19-5-1-2-10-21-19/h1-2,5-10,18,24H,3-4,11-15H2
InChI key
LVXYAFNPMXCRJI-UHFFFAOYSA-N
一般描述
Azaperol is one of the major metabolites of azaperone which is used as a tranquilizer.
应用
Azaperol may be used as an analytical reference standard for the determination of the analyte in:
- Pig tissues by liquid chromatography–tandem mass spectrometry (LC-MS/MS).
- Egg, fish and meat samples by high-resolution liquid chromatography coupled to time-of-flight mass spectrometry (HRLC-TOF-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
推荐产品
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
法律信息
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
D Fluchard et al.
Journal of chromatography. B, Biomedical sciences and applications, 744(1), 139-147 (2000-09-14)
A quick, simple method for quantifying carazolol, azaperol and azaperone is described. Liquid extraction was followed by a clean-up on an Oasis SPE cartridge. The analytes were separated by HPLC and analysed by MS-MS with atmospheric pressure chemical ionisation in
J C Jaen et al.
Journal of medicinal chemistry, 36(24), 3929-3936 (1993-11-26)
The enantiomers of reduced haloperidol (3a), azaperol (3b), and the related compound BMY-14802 (3c) were prepared in high optical purity. The affinity of these compounds for dopamine D2 and D3 receptors, and sigma S1 and S2 sites was determined in
M L Olmos-Carmona et al.
Journal of chromatography. B, Biomedical sciences and applications, 734(1), 113-120 (1999-11-26)
A method for analysis of veterinary tranquillizers in urine using gas chromatography-mass spectrometry (GC-MS) is described. Detection limits are 5 microg/l for ketamine, azaperone and the phenothiazines (chlor-, aceto- and propionylpromazine), 10 microg/l for haloperidol, 20 microg/l for xylazine and
Multi-residue screening of veterinary drugs in egg, fish and meat using high-resolution liquid chromatography accurate mass time-of-flight mass spectrometry.
Peters RJB, et al.
Journal of Chromatography A, 1216(46), 8206-8216 (2009)
L A Adam
Journal of AOAC International, 82(4), 815-824 (1999-08-13)
The method described confirms the use of the tranquilizer azaperone by detecting the parent compound and the metabolically reduced form, azaperol. Both are confirmed in swine liver at a target concentration of 10 ppb by gas chromatography/mass spectrometry (GC/MS) with
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