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Merck
CN

32671

Supelco

卡硝唑

VETRANAL®, analytical standard

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别名:
[2-(2-甲基-5-硝基-咪唑-1-基)乙基]硫代氨基甲酸 O-甲酯
经验公式(希尔记法):
C8H12N4O3S
CAS号:
分子量:
244.27
Beilstein:
620260
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

产品线

VETRANAL®

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

forensics and toxicology
pharmaceutical (small molecule)
veterinary

格式

neat

SMILES字符串

COC(=S)NCCn1c(C)ncc1[N+]([O-])=O

InChI

1S/C8H12N4O3S/c1-6-10-5-7(12(13)14)11(6)4-3-9-8(16)15-2/h5H,3-4H2,1-2H3,(H,9,16)

InChI key

OVEVHVURWWTPFC-UHFFFAOYSA-N

一般描述

Carnidazoles belong to the class of nitroimidazole compounds that are generally utilized for the treatment of various diseases in poultry, cattle and pigs.

应用

Carnidazole may be used as an analytical reference standard for the determination of the analyte in:
  • Eggs by liquid chromatography-tandem mass spectrometry (LC-MS/MS).
  • Environmental water samples by dispersive liquid-liquid microextraction (DLLME), followed by micellar electrokinetic chromatography (MEKC).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

推荐产品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

法律信息

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

CorrosionExclamation mark

警示用语:

Danger

危险声明

危险分类

Eye Dam. 1 - Skin Sens. 1

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


分析证书(COA)

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Novel cation selective exhaustive injection-sweeping procedure for 5-nitroimidazole determination in waters by micellar electrokinetic chromatography using dispersive liquid-liquid microextraction.
Hernandez-Mesa, et al.
Journal of Chromatography A, 1341(46), 65-72 (2014)
[Study of carnidazole (R 25831). A new therapeutic agent for vaginal trichomoniasis].
V Fonzé et al.
Revue medicale de Liege, 34(19), 811-815 (1979-10-01)
P Chaudhuri et al.
European journal of obstetrics, gynecology, and reproductive biology, 10(5), 325-328 (1980-06-01)
A double-blind controlled clinical trial of the new, not yet commercially available drug, carnidazole and tinidazole, was carried out in 77 women with a proven vaginal trichomoniasis. 39 patients and their sexual partners received a single dose of 2 g
Development and validation of a rapid method for the determination and confirmation of 10 nitroimidazoles in animal plasma using liquid chromatography tandem mass spectrometry.
Cronly M, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 877(14-15), 1494-1500 (2009)
F F Franssen et al.
Journal of veterinary pharmacology and therapeutics, 15(4), 409-415 (1992-12-01)
Six out of eight different Trichomonas gallinae strains isolated from racing pigeons proved to be resistant to the nitroimidazole drugs ronidazole, carnidazole and metronidazole. The minimal cytocidal concentration of ronidazole was determined in in vitro experiments. Moreover, a therapeutic dose

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