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等级
analytical standard
质量水平
产品线
VETRANAL®
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
包装形式
neat
SMILES字符串
CC(C(O)=O)c1ccc(CC(C)(C)O)cc1
InChI
1S/C13H18O3/c1-9(12(14)15)11-6-4-10(5-7-11)8-13(2,3)16/h4-7,9,16H,8H2,1-3H3,(H,14,15)
InChI key
UJHKVYPPCJBOSG-UHFFFAOYSA-N
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相关类别
一般描述
2-Hydroxyibuprofen is a well-known human metabolite of ibuprofen. It finds applications as a nonsteroidal and anti-inflammatory drug.
应用
2-Hydroxyibuprofen may be used as a reference standard in the determination of 2-hydroxyibuprofen in urine samples using high-performance liquid chromatography (HPLC) and ultrasound-assisted emulsification microextraction (USAEME) with ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC−MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
法律信息
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 3
Ultrasound-assisted emulsification microextraction combined with ultra-high performance liquid chromatography--tandem mass spectrometry for the analysis of ibuprofen and its metabolites in human urine.
Journal of Pharmaceutical and Biomedical Analysis, 92(2), 193-202 (2014)
Simultaneous quantitative determination of the major phase I and II metabolites of ibuprofen in biological fluids by high-performance liquid chromatography on dynamically modified silica.
Journal of Chromatography. B, Biomedical Sciences and Applications, 696(2), 235-241 (1997)
Journal of separation science, 41(20), 3881-3891 (2018-08-14)
Ibuprofen is widely used in human and veterinary medicine for the treatment of chronic pain as well as rheumatic and musculoskeletal disorders. However, the analgesic and anti-inflammatory properties of Ibuprofen have contributed to frequent drug abuse in equestrian sports. A
Wastewater and Public Health: Bacterial and Pharmaceutical Exposures (2015)
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