32438
帕苯达唑
VETRANAL®, analytical standard
别名:
(5-丁基-1H-苯并咪唑-2-基)氨基甲酸甲酯, 5(6)-丁基-2-苯并咪唑氨基甲酸甲酯
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关于此项目
经验公式（希尔记法）:
C13H17N3O2
化学文摘社编号:
分子量:
247.29
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
238-133-3
MDL number:
InChI
1S/C13H17N3O2/c1-3-4-5-9-6-7-10-11(8-9)15-12(14-10)16-13(17)18-2/h6-8H,3-5H2,1-2H3,(H2,14,15,16,17)
InChI key
YRWLZFXJFBZBEY-UHFFFAOYSA-N
SMILES string
CCCCc1ccc2nc(NC(=O)OC)[nH]c2c1
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Quality Level
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General description
Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
D R Hennessy et al.
Journal of veterinary pharmacology and therapeutics, 15(1), 10-18 (1992-03-01)
The effect of intraruminal administration of parbendazole (PBZ) on the flow rate of bile and the pharmacokinetic behaviour of oxfendazole (OFZ) was examined in sheep. PBZ given at 18, 9 and 4.5 mg/kg resulted in a dose-related reduction in bile
K E Foster et al.
European journal of biochemistry, 163(3), 449-455 (1987-03-16)
The mutant BEN210 of Physarum polycephalum is highly resistant to a number of benzimidazole carbamate agents, including methylbenzimidazole-2-yl-carbamate and parbendazole. The resistance is conferred by the benD210 mutation in a structural gene for beta-tubulin. This mutant allele encodes a beta-tubulin
Hiroshi Sato et al.
The Journal of veterinary medical science, 65(4), 453-457 (2003-05-09)
Larva migrans caused by the common raccoon ascarid, Baylisascaris procyonis, is a zoonotic disease of critical importance in North America. Recently we encountered the first proven outbreak of this disease in Japan in domestic rabbits (Oryctolagus cuniculus) in a small
E Lacey et al.
Molecular and biochemical parasitology, 19(2), 171-181 (1986-05-01)
The binding of tritiated benzimidazoles (BZs)-albendazole, parbendazole, oxibendazole, mebendazole, oxfendazole and fenbendazole-to crude tubulin extracts from BZ-susceptible and -resistant Haemonchus contortus has been examined. For all BZs, the binding was substantially lower in the resistant isolate. The extent of this
N C Sangster et al.
The Journal of parasitology, 71(5), 645-651 (1985-10-01)
Benzimidazole treatment produced greater effects on microtubule-dependent acetylcholinesterase secretion, the presence of microtubules in intestinal cells, and colchicine binding in susceptible compared with benzimidazole-resistant Trichostrongylus colubriformis. In addition, the binding of benzimidazoles was markedly reduced in preparations from the latter
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