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Merck
CN

32087

Cylindrospermopsin solution

10 μg/mL in H2O, PESTANAL®, analytical standard

别名:

6-[(R)-Hydroxy[(2aS,3R,4S,5aS,7R)-2,2a,3,4,5,5a,6,7-octahydro-3-methyl-4-(sulfooxy)-1H-1,8,8b-triazaacenaphthylen-7-yl]methyl]-2,4(1H,3H)-pyrimidinedione

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关于此项目

经验公式（希尔记法）:
C15H21N5O7S
化学文摘社编号:
143545-90-8
分子量:
415.42
MDL number:
MFCD01939922
UNSPSC Code:
41116107
NACRES:
NA.24

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产品名称

Cylindrospermopsin solution, 10 μg/mL in H2O, PESTANAL®, analytical standard

SMILES string

C[C@H]1[C@H](C[C@@H]2C[C@@H](N=C3NC[C@H]1N23)[C@@H](O)C4=CC(=O)NC(=O)N4)OS(O)(=O)=O

InChI

1S/C15H21N5O7S/c1-6-10-5-16-14-17-8(13(22)9-4-12(21)19-15(23)18-9)2-7(20(10)14)3-11(6)27-28(24,25)26/h4,6-8,10-11,13,22H,2-3,5H2,1H3,(H,16,17)(H,24,25,26)(H2,18,19,21,23)/t6-,7+,8-,10-,11+,13+/m1/s1

InChI key

LHJPHMKIGRLKDR-YUQKHPEDSA-N

grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

concentration

10 μg/mL in H2O

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

Quality Level

100

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN7219
BCCM5156
BCCL9813
BCCK5291
BCCJ1202

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Fiona M Young et al.
Toxicology in vitro : an international journal published in association with BIBRA, 26(5), 656-662 (2012-03-21)
The blue-green algal toxin cylindrospermopsin (CYN) inhibits protein synthesis, and CYP450 enzymes metabolise CYN to cytotoxic endproducts. Human chorionic gonadotrophin (hCG) stimulates the de novo synthesis of StAR and CYP450 aromatase. Human IVF-derived granulosa cells (GC) (n=7) were exposed to
Joanna Mankiewicz-Boczek et al.
FEMS microbiology letters, 326(2), 173-179 (2011-11-19)
The presence of toxigenic cyanobacteria capable of biosynthesis of cylindrospermopsin (CYN) was measured in 24 water samples collected from the lakes Bytyńskie (BY) and Bnińskie (BN) in the Western Poland. The study also covered analysis of toxigenicity and production of
Daniel Gutiérrez-Praena et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 53, 139-152 (2012-12-04)
Microcystins (MCs) and cylindrospermopsin (CYN) are among the cyanotoxins which occur naturally, produced by different cyanobacteria species when they grow or proliferate under favorable environmental conditions. From a toxicological point of view, their relevance is due to the deleterious effects
Remedios Guzmán-Guillén et al.
Talanta, 100, 356-363 (2012-11-13)
The occurrence of cyanobacterial blooms in aquatic environments is increasing in many regions of the world due to progressive eutrophication of water bodies. Because of the production of toxins such as Cylindrospermopsin (CYN), contamination of water with cyanobacteria is a
Henar López-Alonso et al.
Chemical research in toxicology, 26(2), 203-212 (2012-12-29)
The increasing presence of cyanotoxin producers in several regions of the world is hazardous for humans and animals. Cylindrospermopsin (CYN) is nowadays recognized as a widely distributed freshwater cyanobacterial toxin. This toxin has been shown to induce protein synthesis inhibition
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