31737
磺胺甲噁唑
VETRANAL®, analytical standard
别名:
4-氨基- N -（5-甲基-3-异恶唑基）苯磺酰胺, N 1 -（5-甲基异恶唑-3-基）磺胺
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关于此项目
经验公式（希尔记法）:
C10H11N3O3S
化学文摘社编号:
分子量:
253.28
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
211-963-3
Beilstein/REAXYS Number:
6732984
MDL number:
InChI key
JLKIGFTWXXRPMT-UHFFFAOYSA-N
InChI
1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
SMILES string
Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
Quality Level
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General description
磺胺甲恶唑是一种抑菌抗生素，用于治疗人类的球虫病、腹泻和胃肠炎，也是一种已知的兽药。磺胺甲恶唑与甲氧苄啶合用可有效治疗感染性肺炎。磺胺甲恶唑通过阻断叶酸代谢，产生协同抗菌活性起作用。
Application
有关合适的仪器技术的更多信息，请参阅产品′的检验报告。想要获得更多支持，请联系技术服务部。
磺胺甲恶唑可用作标准品测定以下物质中的分析物：
- 牛乳，通过高效液相色谱法。
- 药物制剂和生物样品，通过毛细管电泳（CE）和末端柱电化学检测（EC）。
Other Notes
在我们的NMR在线平台ChemisTwin®上可以找到本品对应的数字化标准物质。您可使用ChemisTwin®上的数字等效品鉴定您的样品并进行定量分析（使用数字化外标）。可查看该物质的NMR谱图，只需点击几次鼠标，就能进行在线样品比对。欢迎点击了解更多，开启免费试用之旅。
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 2
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
High-performance liquid chromatography method for the simultaneous determination of sulfamethoxazole and trimethoprim in bovine milk using an on-line clean-up column.
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Journal of Hazardous Materials, 150(3), 790-794 (2008)
Determination of sulfadiazine and sulfamethoxazole by capillary electrophoresis with end-column electrochemical detection.
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Ming Xie et al.
Water research, 47(13), 4567-4575 (2013-06-15)
The impact of humic acid fouling on the membrane transport of two pharmaceutically active compounds (PhACs) - namely carbamazepine and sulfamethoxazole - in forward osmosis (FO) was investigated. Deposition of humic acid onto the membrane surface was promoted by the
Trimethoprim-sulfamethoxazole-associated aseptic meningitis: case reports and review of the literature.
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The American journal of medicine, 87(3), 332-338 (1989-09-01)
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