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Merck
CN

31640

Supelco

4,4′-二氨基二苯甲烷

analytical standard

别名:

4,4′-亚甲基双苯胺, MDA

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About This Item

经验公式(希尔记法):
C13H14N2
CAS号:
分子量:
198.26
Beilstein:
474706
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

88-92 °C

应用

cleaning products
cosmetics
food and beverages
personal care

包装形式

neat

SMILES字符串

Nc1ccc(Cc2ccc(N)cc2)cc1

InChI

1S/C13H14N2/c14-12-5-1-10(2-6-12)9-11-3-7-13(15)8-4-11/h1-8H,9,14-15H2

InChI key

YBRVSVVVWCFQMG-UHFFFAOYSA-N

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一般描述

4,4′-Diaminodiphenylmethane (MDA) is an aromatic diamine, which finds industrial applications as a precursor in the manufacturing of polyurethane products, isocyanates, polyisocyanates, etc. It is also used as a hardener in the production of epoxy resins and elastomers.
4,4′-Diaminodiphenylmethane is a curing agent for epoxy resins. It is prepared from formaldehyde aniline when heated with aniline hydrochloride and aniline.

应用

4,4′-Diaminodiphenylmethane is used as an analytical reference standard for the quantification of the analyte in the following:
  • Urine samples using gas-chromatography coupled to mass spectrometry (GC-MS).
  • Hepatic microsomal incubation mixture from rabbits using high-performance liquid chromatography-plasma spray mass spectrometry (HPLC-PSP-MS), offline HPLC with fast atom bombardment mass spectrometry (FAB-MS) and fast atom bombardment tandem mass spectrometry (FAB-MS/MS).

It is reported to be used in the synthesis of amino modified multi-walled carbon nanotubes/polydimethylsiloxane, which serves as a coating for the stir bar sorptive extraction (SBSE) of phenols in environmental samples, followed by analysis using high performance liquid chromatography with ultraviolet detection (HPLC-UV).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Carc. 1B - Muta. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 1

靶器官

Liver, Liver,eye - retina

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

429.8 °F - closed cup

闪点(°C)

221 °C - closed cup

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

危险化学品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

4, 4'-Diaminodiphenylmethane.
Gooch, Jan W.
Encyclopedic Dictionary of Polymers, 204-205 (2011)
Hexamethylene diisocyanate, 2, 4?toluene diisocyanate, 2, 6?toluene diisocyanate, isophorone diisocyanate and 4, 4??methylene diphenyl diisocyanate?Determination of hexamethylenediamine, 2, 4?toluenediamine, 2, 6?toluenediamine, isophoronediamine and 4, 4??methylenedianiline in urine using gas chromatography?mass spectrometry [Biomonitoring Methods, 2017]
The MAK?Collection for Occupational Health and Safety: Annual Thresholds and Classifications for the Workplace, 2(3), 1415-1435 (2002)
Characterization of biliary conjugates of 4, 4?-methylenedianiline in male versus female rats
Toxicology and Applied Pharmacology, 232(2), 190-202 (2008)
Amino modified multi-walled carbon nanotubes/polydimethylsiloxane coated stir bar sorptive extraction coupled to high performance liquid chromatography-ultraviolet detection for the determination of phenols in environmental samples
Journal of Chromatography A, 1300(42), 165-172 (2013)
Identification of metabolites of 4, 4'-diaminodiphenylmethane (methylene dianiline) using liquid chromatographic and mass spectrometric techniques
Journal of Chromatography. B, Biomedical Sciences and Applications, 583(1), 63-76 (1992)

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