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Merck
CN

31626

杆菌肽 A

VETRANAL®, analytical standard, main stereoisomer ~50 %

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经验公式(希尔记法):
C66H103N17O16S
分子量:
1422.69
UNSPSC Code:
41116107
PubChem Substance ID:
EC Number:
245-115-9
NACRES:
NA.24
E Number:
E700
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SMILES string

CC[C@H](C)[C@H](N)C1=N[C@@H](CS1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)NC([C@@H](C)CC)C(=O)N[C@H]2CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H](Cc4ccccc4)NC(=O)C(NC(=O)[C@@H](CCCN)NC2=O)[C@@H](C)CC

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

composition

main stereoisomer, ~50%

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

Quality Level

General description

杆菌肽是一种由枯草芽孢杆菌地衣芽孢杆菌产生的多肽抗生素。杆菌肽A是杆菌肽商业生产的主要微生物活性组分。

Application

2009年12月22日颁布的欧委会法规(EU) No 37/2010规定了药物活性物质及关于动物源性食品最大残留物限制的分类
有关合适的仪器技术的更多信息,请参阅产品的分析证书。想要获得更多支持,请联系技术服务部。

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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K Harada et al.
Journal of chromatography, 538(1), 203-212 (1991-01-18)
The major components of bacitracin were separated and purified using high-speed counter-current chromatography (HSCCC). A systematic search for optimum two-phase solvent systems resulted in two systems: chloroform-ethanol-methanol-water (5:3:3:4) and chloroform-ethanol-water (5:4:3). These were selected based on the determination of the
F Drabløs et al.
Biochimica et biophysica acta, 1431(2), 433-442 (1999-06-03)
Bacitracin is a dodecapeptide antibiotic produced by Bacillus sp. The antibacterial activity depends upon the peptide binding a divalent metal. Hitherto, the exact coordination of the cation has not been established. In particular the role played by the sulphur and
Juma D Bridgewater et al.
Analytical chemistry, 78(7), 2432-2438 (2006-04-04)
We have identified conditions that allow metal-catalyzed oxidation (MCO) reactions and mass spectrometry (MS) to correctly identify binding sites of first-row transition metal ions to model peptides. This work extends the applicability of the MCO/MS method to metals other than
Massimo Castagnola et al.
Electrophoresis, 25(6), 846-852 (2004-03-09)
Thermodynamics of the binding of Ni(2+), Cu(2+) and Zn(2+) to bacitracin A(1) was studied by capillary electrophoresis measuring the peptide effective mobility at different pH in the presence of increasing concentration of the three ligands. The affinity follows the order
Cindy Govaerts et al.
Rapid communications in mass spectrometry : RCM, 17(12), 1366-1379 (2003-06-18)
A selective reversed-phase liquid chromatography/mass spectrometry (LC/MS(n)) method is described for the characterization of related compounds in commercial bacitracin samples. Mass spectral data for these polypeptide antibiotics were acquired on a LCQ ion trap mass spectrometer equipped with an electrospray

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