31618
2-萘胺
analytical standard
别名:
β-氨基萘, 2-氨基萘
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关于此项目
线性分子式:
C10H7NH2
化学文摘社编号:
分子量:
143.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
202-080-4
Beilstein/REAXYS Number:
3939429
MDL number:
InChI key
JBIJLHTVPXGSAM-UHFFFAOYSA-N
InChI
1S/C10H9N/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,11H2
SMILES string
Nc1ccc2ccccc2c1
grade
analytical standard
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
bp
306 °C (lit.)
mp
111-113 °C (lit.)
density
1.061 g/mL at 25 °C (lit.)
application(s)
cleaning products
cosmetics
food and beverages
personal care
format
neat
Quality Level
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General description
2-Naphthylamine is a carcinogenic aromatic amine which induces tumor in urinary bladder.
Application
2-Naphthylamine has been used as reference standard during isolation and identification of urinary metabolites using preparative thin-layer chromatography and gas-liquid chromatography/mass spectral analysis.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Disclaimer
仅面向专业用户。注意 — 避免接触 — 使用前请了解特别说明。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 1A
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
危险化学品
此项目有
Metabolic conversion of 1-and 2-nitronaphthalene to 1-and 2-naphthylamine in the rat.
Johnson, Dale E., and Herbert H. Cornish.
Toxicology and Applied Pharmacology, 46.3, 549-553 (1978)
Formation of urothelial and hepatic DNA adducts from carcinogen 2-naphthylamine.
Kadlubar FF
Carcinogenesis, 2(5), 467-470 (1981)
Weimei Sun et al.
The Journal of pharmacology and experimental therapeutics, 375(3), 510-521 (2020-10-10)
Inhibition of the serine protease enteropeptidase (EP) opens a new avenue to the discovery of chemotherapeutics for the treatment of metabolic diseases. Camostat has been used clinically for treating chronic pancreatitis in Japan; however, the mechanistic basis of the observed
Dylan M Owen et al.
Nature communications, 3, 1256-1256 (2012-12-06)
Lipid microdomains are postulated to regulate many membrane-associated processes but have remained highly controversial. Here we provide the first direct evidence that the plasma membrane of intact, live cells is comprised of a sub-resolution mixture of approximately 76% ordered and
Carlos de la Haba et al.
Biochimica et biophysica acta, 1828(2), 357-364 (2012-09-04)
Plasma membrane is one of the preferential targets of reactive oxygen species which cause lipid peroxidation. This process modifies membrane properties such as membrane fluidity, a very important physical feature known to modulate membrane protein localization and function. The aim
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