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经验公式(希尔记法):
C16H19N3O5S · 3H2O
化学文摘社编号:
分子量:
419.45
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
7507120
产品名称
阿莫西林 三水合物, VETRANAL®, analytical standard
InChI key
MQXQVCLAUDMCEF-CWLIKTDRSA-N
SMILES string
O.O.O.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(O)=O
InChI
1S/C16H19N3O5S.3H2O/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7;;;/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24);3*1H2/t9-,10-,11+,14-;;;/m1.../s1
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
clinical testing
format
neat
storage temp.
2-8°C
Quality Level
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Application
Amoxicillin trihydrate may be used as reference standard in stability study of Amoxicillin-Clavulanate in BACTEC Medium performed using HPLC.3
Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
Amoxicillin trihydrate is a β-lactam antibiotic. It is a broad-spectrum drug mostly administered orally.1 It is used to treat bacterial infections mainly caused by susceptible microorganisms.2
Chemical structure: ß-lactam
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
涉药品监管产品
此项目有
Claudia Foti et al.
Molecules (Basel, Switzerland), 25(14) (2020-07-12)
A potentiometric and UV spectrophotometric investigation on Mn2+-ampicillin and Mn2+-amoxicillin systems in NaCl aqueous solution is reported. The potentiometric measurements were carried out under different conditions of temperature (15 ≤ t/°C ≤ 37). The obtained speciation pattern includes two species
Qian Zhao et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 67(7), 1605-1611 (2013-04-05)
This paper investigated the effects of selected common chemical species in natural waters (HCO3(-), NO3(-) and humic acids (HA)) on the photodegradation of amoxicillin (AMO) under simulated irradiation using a 300 W xenon lamp. Quenching experiments were carried out to
Fanny B Morel et al.
Neonatology, 103(3), 182-189 (2013-02-26)
It is suggested that antibiotherapy in infancy might program adult body composition and thus could be a determinant of obesity risk. Although not convincingly substantiated by existing literature, this assumption is plausible since antibiotics affect intestinal microbiota, whose composition in
Yu-Hsin Lin et al.
Biomaterials, 34(18), 4466-4479 (2013-03-19)
Helicobacter pylori is a significant human pathogen that recognizes specific carbohydrate receptors, such as the fucose receptor, and produces the vacuolating cytotoxin, which induces inflammatory responses and modulates the cell-cell junction integrity of the gastric epithelium. The clinical applicability of
Enrique Gómez et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 110(4), 267-273 (2013-03-29)
Although allergic drug reactions have been considered to be immediate (IgE mediated) or delayed (T-cell effector mechanisms), accelerated reactions have also been defined; however, they have not been sufficiently studied. To study the mechanisms involved in accelerated reactions to amoxicillin.
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