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Merck
CN

30552

Supelco

莫能菌素甲酯

Selectophore, ≥97.0% (TLC)

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别名:
甲基莫能菌素酯
经验公式(希尔记法):
C37H64O11
CAS号:
分子量:
684.90
Beilstein:
3641733
UNSPSC代码:
26111700
NACRES:
NB.61

等级

for ion-selective electrodes

质量水平

产品线

Selectophore

检测方案

≥97.0% (TLC)

储存温度

2-8°C

SMILES字符串

CC[C@]1(CCC(O1)[C@]2(C)CC[C@]3(C[C@H](O)[C@@H](C)C(O3)[C@@H](C)[C@@H](OC)[C@H](C)C(=O)OC)O2)C4OC(C[C@@H]4C)C5O[C@@](O)(CO)[C@H](C)C[C@@H]5C

InChI

1S/C37H64O11/c1-11-35(32-21(3)17-27(44-32)29-20(2)16-22(4)37(41,19-38)47-29)13-12-28(45-35)34(8)14-15-36(48-34)18-26(39)23(5)31(46-36)24(6)30(42-9)25(7)33(40)43-10/h20-32,38-39,41H,11-19H2,1-10H3/t20-,21+,22+,23+,24+,25+,26-,27-,28+,29-,30-,31-,32-,34+,35-,36+,37-/m0/s1

InChI key

PFRZSHIENRKVSE-RJTHVKINSA-N

一般描述

Monensin, is an antibiotic produced by Streptomyces cinnamonensis. It is a naturally occurring ionophore. It has an acyclic polyether sequence and a terminal carboxylic acid moiety. It has the ability to effectively carry protons and cations through the cell membrane, hence it adequately harbours Na+ into a characteristic pseudoactivity, thereby effectively transporting it across a bio-membrane. It also forms stable complexes with k+, Rb+ and Ag+; hence it can be chemically modified to form cation-binding sites, thereby attaining transport functionalities.
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应用


  • The selectivity of membrane ion-selective electrodes: This research explores the use of temperature variations to adjust the selectivity of ion-selective electrodes, utilizing Monensin methyl ester as a key component for sodium ion detection (Zahran et al., 2010).

  • Spectroscopic and semiempirical studies of a proton channel formed by the methyl ester of monensin A.: This paper presents a detailed analysis of the proton channel properties of Monensin methyl ester through spectroscopic and computational methods, highlighting its potential in analytical chemistry applications (Huczyński et al., 2006).

  • Ion chromatography detector based on solid-state ion-selective electrode array.: The development of an ion chromatography detector employing solid-state ion-selective electrodes, with Monensin methyl ester playing a crucial role in sodium ion detection, is detailed in this study (Lee et al., 2000).

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

法律信息

Selectophore is a trademark of Merck KGaA, Darmstadt, Germany

象形图

Skull and crossbones

警示用语:

Danger

危险声明

预防措施声明

危险分类

Acute Tox. 3 Oral

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

新产品

分析证书(COA)

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José N Sousa et al.
European journal of mass spectrometry (Chichester, England), 13(3), 191-198 (2007-09-21)
This paper reports the first comparative study of the gas-phase fragmentation chemistry of monensin in negative ion mode electrospray and nanoelectrospray tandem mass spectrometry. The fragmentation was observed to occur at lower energies in nanoelectrospray than electrospray. The major product
Adam Huczyñski et al.
The journal of physical chemistry. B, 110(31), 15615-15623 (2006-08-04)
Monensin A is an ionophore able to carry protons and cations through the cell membrane. Its methyl ester (MON1) and its hydrates have been studied in acetonitrile, and its deuterated analogue by Fourier transform infrared (FTIR) and (1)H and (13)C
Specific Ag+ ion-transport properties of functionalized biological monensin ionophore.
Tsukube H and Sohmiya H.
Inorgorganica Chimica Acta, 166 (1), 27-29 (1989)
Biosynthesis of monensin.
Day LE
Antimicrobial Agents and Chemotherapy, 4 (4), 410-414 (1973)
Spectroscopic and semiempirical studies of a proton channel formed by the methyl ester of monensin A.
Huczynski A
The Journal of Physical Chemistry B, 110 (31), 15615-15623 (2006)

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