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Merck
CN

301310

Sigma-Aldrich

2-Ethyl-2-thiopseudourea hydrobromide

98%

别名:

S-Ethylisothiourea hydrobromide

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About This Item

线性分子式:
C2H5SC(=NH)NH2 · HBr
CAS号:
分子量:
185.09
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:

方案

98%

表单

powder or crystals

mp

88-90 °C (lit.)

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

Br.CCSC(N)=N

InChI

1S/C3H8N2S.BrH/c1-2-6-3(4)5;/h2H2,1H3,(H3,4,5);1H

InChI key

SWXXKWPYNMZFTE-UHFFFAOYSA-N

应用

Reagent used in the synthesis of pyrimidines.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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R L Rairigh et al.
The Journal of clinical investigation, 101(1), 15-21 (1998-02-14)
Nitric oxide (NO) produced by NO synthase (NOS) modulates fetal pulmonary vascular tone and contributes to the fall in pulmonary vascular resistance (PVR) at birth. Although the inducible (type II) NOS isoform is present in human and rat fetal lungs
Lior Sasson et al.
Cardiology, 111(3), 181-187 (2008-04-25)
Hypotension is common immediately following cardiopulmonary bypass. Experimentally, MTR-105 (S-ethylisothiuronium diethylphosphate), a fast-acting synthetic nitric oxide synthase inhibitor, rapidly increases blood pressure. The purpose of the current study was to assess the influence of MTR-105 on hemodynamics early after cardiopulmonary
F Squadrito et al.
British journal of pharmacology, 119(1), 23-28 (1996-09-01)
1. The aim of this study was to compare the effects of an intravenous infusion of a potent and non selective nitric oxide synthase inhibitor S-ethylisothiourea (Ethyl-TU) with that of a nitric oxide (NO) donor on the pathological sequelae associated
H G Seo et al.
Journal of biochemistry, 119(3), 553-558 (1996-03-01)
Nitric oxide (NO) is synthesized from L-arginine by three isoforms of NO synthase (NOS). It is essential to suppress the function of the inducible isoform (macNOS) for amelioration of some inflammatory diseases in which the cytotoxic effect of NO is
J P Spiers et al.
British journal of pharmacology, 130(6), 1275-1282 (2000-07-25)
1. The contractile effects of endothelin-1, isoprenaline and extracellular calcium were assessed on ventricular cardiomyocytes isolated from lipopolysaccharide-treated rats. The involvement of nitric oxide was investigated using dexamethasone (in vivo) and ethyl isothiourea (in vitro). 2. Male Wistar rats (n=70)

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