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Merck
CN

21980

Sigma-Aldrich

测心绿

for microscopy

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别名:
吲哚菁绿, 福氏绿, 靛氰绿
经验公式(希尔记法):
C43H47N2NaO6S2
CAS号:
分子量:
774.96
Beilstein:
4115884
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
MA.02

等级

for microscopy

质量水平

形式

powder

颜色

green to very dark green

溶解性

water: 0.01 g/10 mL

ε (消光系数)

≥115 at 386-396 nm in water
≥2000 at 774-784 nm in water
≥900 at 712-722 nm in water

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

[Na+].CC1(C)/C(=C\C=C\C=C\C=C\C2=[N+](CCCCS([O-])(=O)=O)c3ccc4ccccc4c3C2(C)C)N(CCCCS([O-])(=O)=O)c5ccc6ccccc6c15

InChI

1S/C43H48N2O6S2.Na/c1-42(2)38(44(28-14-16-30-52(46,47)48)36-26-24-32-18-10-12-20-34(32)40(36)42)22-8-6-5-7-9-23-39-43(3,4)41-35-21-13-11-19-33(35)25-27-37(41)45(39)29-15-17-31-53(49,50)51;/h5-13,18-27H,14-17,28-31H2,1-4H3,(H-,46,47,48,49,50,51);/q;+1/p-1

InChI key

MOFVSTNWEDAEEK-UHFFFAOYSA-M

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一般描述

Cardiogreen 是一种用于显微镜检查的染料。该染料在与还原和氧合血红蛋白相同的波长下具有最大的消光度,使得可以记录血液中的氧饱和度。这种染料没有副作用。

应用

将 Cardiogreen 注射到动物体内,用于动态光学成像系统,以研究捕获体内生物分布动力学的能力。

包装

无底玻璃瓶。内含物装在插入的融合锥内。

其他说明

用于肝功能测定的诊断助剂

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

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  1. How does the storage temperature relate to shipping conditions?

    The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment. See Shipping and Storage for more information.

  2. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  3. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  4. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  5. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  6. Has Cardiogreen been used for in vivo optical imaging studies?

    We do not subject this product to in vivo testing. However, one study documents the use of the product in a study with mice:For optical imaging, mice were injected intravenously with a mixture of 0.05 ml of 260 μM ICG (Cardiogreen) and 0.05 ml of 360 μM DTR (70,000 MW, Invitrogen) in saline (equivalent to 0.4 mg per kg or 7.4 μM initial concentration in blood).

  7. Does Cardiogreen dissolve equally well in saline and in water?

    Each lot is tested for solubility in hot water at 1 mg/mL. We have found that Sigma Product No. I2633 (which has the same CAS number as Product No. 21980) dissolves in water at 1 mg/mL without heating. Further dilute in saline to prepare an isotonic solution.

  8. How long can I store a solution of Cardiogreen after it has been prepared?

    Sigma-Aldrich recommends that solutions be prepared fresh and not stored. Solutions "are stable only for a few hours and cannot be kept overnight." See: Sigma-Aldrich Handbook of Dyes, Stains, and Indicators, Green, F. ed., p. 407.

  9. Can Product No. I2633, Cardiogreen, be used as a biological stain?

    Limited absorbance in the visible region practically precludes the use of Indocyanine Green as a biological stain. See: Sigma-Aldrich Handbook of Dyes, Stains, and Indicators, Green, F. ed., p. 407.

  10. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

C.M. Leevy et al.
Probl. Liver Dis. (Review), 42-42 (1979)
Determination of cardiac output with cardio green in a direct writing colorimeter.
B HYSING et al.
Scandinavian journal of clinical and laboratory investigation, 14, 430-434 (1962-01-01)
K Igari et al.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 46(4), 460-465 (2013-08-27)
We performed indocyanine green angiography (ICGA) in patients with peripheral arterial disease (PAD), and established a method for the quantitative measurement of appropriate parameters to assess peripheral perfusion and the applicability of ICGA tests. Twenty-one patients with PAD underwent revascularization
Toshiki Endo et al.
Journal of neurosurgery. Spine, 18(5), 443-449 (2013-03-12)
The characteristics and efficacy of indocyanine green (ICG) videoangiography in cavernous malformation (CM) have not been fully elucidated. The purpose of this paper is to examine the potential utility of ICG videoangiography in the surgical treatment of intramedullary CMs. The
Elizabeth M C Hillman et al.
Nature photonics, 1(9), 526-530 (2008-11-01)
Optical molecular imaging in small animals harnesses the power of highly specific and biocompatible contrast agents for drug development and disease research1-7. However, the widespread adoption of in vivo optical imaging has been inhibited by its inability to clearly resolve

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