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Merck
CN

21192

钙离子载体 I

Selectophore, function tested, ≥99.0%

别名:

(-)-(R,R)-N,N′-二-[11-(乙氧羰基)十一烷基]-N,N′,4,5-四甲基-3,6-二氧杂辛烷-二酰胺, ETH 1001, 二乙基N,N′-[(4R,5R)-4,5-二甲基-1,8-二氧代-3,6-二氧杂亚辛基]双(12-甲氨基月桂酸酯)

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关于此项目

经验公式(希尔记法):
C38H72N2O8
化学文摘社编号:
分子量:
684.99
UNSPSC Code:
26111700
NACRES:
NB.61
PubChem Substance ID:
EC Number:
261-449-8
Beilstein/REAXYS Number:
2343275
MDL number:
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产品名称

钙离子载体 I, Selectophore, function tested, ≥99.0%

InChI key

CJAONIOAQZUHPN-KKLWWLSJSA-N

InChI

1S/C38H72N2O8/c1-7-45-37(43)27-23-19-15-11-9-13-17-21-25-29-39(5)35(41)31-47-33(3)34(4)48-32-36(42)40(6)30-26-22-18-14-10-12-16-20-24-28-38(44)46-8-2/h33-34H,7-32H2,1-6H3/t33-,34-/m1/s1

SMILES string

CCOC(=O)CCCCCCCCCCCN(C)C(=O)CO[C@H](C)[C@@H](C)OCC(=O)N(C)CCCCCCCCCCCC(=O)OCC

description

for ion-selective electrodes

product line

Selectophore

assay

≥99.0% (HPLC)
≥99.0%

quality

function tested

Quality Level

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Application

选应用实例
已有试验研究采用电离层I (ETH 1001)测定大鼠缺氧缺血时细胞内外钙离子变化。

General description

请访问我们的 传感器应用页面 以了解更多信息。

Other Notes

作为膜电极中的离子载体,用于测定Ca2+离子的活性;可用于生物膜的转运研究

Packaging

无底玻璃瓶。内容物在插入式融锥内。

Legal Information

Selectophore is a trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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I A Silver et al.
The Journal of general physiology, 95(5), 837-866 (1990-05-01)
Changes in intra- and extracellular free calcium concentration were evaluated with ion-selective microelectrodes during periods of anoxia and ischemia in three different regions of intact rat brain. Recordings stable for at least 2 min and in most cases for 4-6
W. Simon et al.
Annals of the New York Academy of Sciences, 307, 52-52 (1978)
Rita I Jabr et al.
Pflugers Archiv : European journal of physiology, 468(11-12), 1945-1955 (2016-10-21)
Cardiac arrhythmias are associated with raised intracellular [Ca2+] and slowed action potential conduction caused by reduced gap junction (GJ) electrical conductance (Gj). Ventricular GJs are composed of connexin proteins (Cx43), with Gj determined by Cx43 phosphorylation status. Connexin phosphorylation is
P Caroni et al.
Biochimica et biophysica acta, 470(3), 437-445 (1977-11-01)
The effect of a synthetic neutral ligand on the Ca2+ permeability of several biological membranes has been investigated. The ligand had been previously shown to possess Ca2+ -ionophoric activities in artificial phospholipid membranes. The neutral ionophore is able to transport
Anna Kisiel et al.
Talanta, 220, 121358-121358 (2020-09-16)
An alternative optical signal transduction mechanism for ion-selective optodes is proposed. The nanostructural sensors benefit from ion-selective reversing aggregation caused quenching yielding turn-on, bright and highly stable optical signals. Selective incorporation of analyte results in transformation of the polymer dye

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Sigma-Aldrich.com presents an article on Selectophore Ionophores

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