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Merck
CN

201316

Sigma-Aldrich

喹哪啶红

Dye content 95 %

别名:

2-[4-(二甲基氨基)苯乙烯]-1-乙基喹啉碘化物

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About This Item

经验公式(希尔记法):
C21H23IN2
CAS号:
分子量:
430.33
Beilstein:
3798055
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47

表单

powder or crystals

质量水平

组成

Dye content, 95%

技术

titration: suitable

溶解性

ethanol: 1 mg/mL, clear, dark red

λmax

528 nm

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

[I-].CC[n+]1c(\C=C\c2ccc(cc2)N(C)C)ccc3ccccc13

InChI

1S/C21H23N2.HI/c1-4-23-20(16-12-18-7-5-6-8-21(18)23)15-11-17-9-13-19(14-10-17)22(2)3;/h5-16H,4H2,1-3H3;1H/q+1;/p-1

InChI key

JOLANDVPGMEGLK-UHFFFAOYSA-M

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应用

喹哪啶红已被用作α1-酸糖蛋白(AAG)的荧光探针。

生化/生理作用

喹哪啶红(2-(对-二甲基氨基苯乙烯基)喹啉乙硫醇)是一种非常暗红色或红黑色的粉末。它主要用于调节细胞增殖、与淀粉样蛋白积累有关的疾病的诊断试剂、检测酶活性和牙科漂白材料。此外,喹哪啶红还涉及异常性疼痛和病毒感染性疾病的治疗。在pH 1.4时其呈无色,在pH 3.2时呈红色。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Selective plasma protein binding of antimalarial drugs to a1-acid glycoprotein
Zsila F
Bioorganic & Medicinal Chemistry, 3759-3772 (2008)
Cationic Drug Pharmacokinetics in Diseased Livers Determined by Fibrosis Index, Hepatic Protein Content, Microsomal Activity, and Nature of Drug
Hung D Y
Journal of Pharmacology and Experimental Therapeutics, 301, 1079-1087 (2002)
Paul Zuck et al.
Analytical biochemistry, 342(2), 254-259 (2005-06-14)
Miniaturization of high-throughput screening (HTS) assays has several obvious advantages, including increased throughput and lower cost by reduction in reagent consumption. Although absorbance assays are widely used in research laboratories, their application for HTS in a low-volume format has been
A I Ivanov et al.
Clinical and experimental medicine, 2(3), 147-155 (2002-11-26)
The acute-phase response alters the composition of carrier proteins in plasma, which may affect the blood deposition and transport of biomediators and drugs. The effect of the acute-phase response on the ligand binding ability of plasma was studied in leukemic
H Imamura et al.
Biological & pharmaceutical bulletin, 16(9), 926-929 (1993-09-01)
We attempted to develop a fluorescent probe superior to conventional ones (8-anilino-1-naphthalenesulfonate and auramine O) for use in the study of drug-binding sites on alpha 1-acid glycoprotein (AGP). It was found that quinaldine red (QR) strongly bound to AGP and

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