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表单
powder or crystals
质量水平
组成
Dye content, 95%
技术
titration: suitable
溶解性
ethanol: 1 mg/mL, clear, dark red
λmax
528 nm
应用
diagnostic assay manufacturing
hematology
histology
储存温度
room temp
SMILES字符串
[I-].CC[n+]1c(\C=C\c2ccc(cc2)N(C)C)ccc3ccccc13
InChI
1S/C21H23N2.HI/c1-4-23-20(16-12-18-7-5-6-8-21(18)23)15-11-17-9-13-19(14-10-17)22(2)3;/h5-16H,4H2,1-3H3;1H/q+1;/p-1
InChI key
JOLANDVPGMEGLK-UHFFFAOYSA-M
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应用
喹哪啶红已被用作α1-酸糖蛋白(AAG)的荧光探针。
生化/生理作用
喹哪啶红(2-(对-二甲基氨基苯乙烯基)喹啉乙硫醇)是一种非常暗红色或红黑色的粉末。它主要用于调节细胞增殖、与淀粉样蛋白积累有关的疾病的诊断试剂、检测酶活性和牙科漂白材料。此外,喹哪啶红还涉及异常性疼痛和病毒感染性疾病的治疗。在pH 1.4时其呈无色,在pH 3.2时呈红色。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Selective plasma protein binding of antimalarial drugs to a1-acid glycoprotein
Zsila F
Bioorganic & Medicinal Chemistry, 3759-3772 (2008)
Cationic Drug Pharmacokinetics in Diseased Livers Determined by Fibrosis Index, Hepatic Protein Content, Microsomal Activity, and Nature of Drug
Hung D Y
Journal of Pharmacology and Experimental Therapeutics, 301, 1079-1087 (2002)
Paul Zuck et al.
Analytical biochemistry, 342(2), 254-259 (2005-06-14)
Miniaturization of high-throughput screening (HTS) assays has several obvious advantages, including increased throughput and lower cost by reduction in reagent consumption. Although absorbance assays are widely used in research laboratories, their application for HTS in a low-volume format has been
A I Ivanov et al.
Clinical and experimental medicine, 2(3), 147-155 (2002-11-26)
The acute-phase response alters the composition of carrier proteins in plasma, which may affect the blood deposition and transport of biomediators and drugs. The effect of the acute-phase response on the ligand binding ability of plasma was studied in leukemic
H Imamura et al.
Biological & pharmaceutical bulletin, 16(9), 926-929 (1993-09-01)
We attempted to develop a fluorescent probe superior to conventional ones (8-anilino-1-naphthalenesulfonate and auramine O) for use in the study of drug-binding sites on alpha 1-acid glycoprotein (AGP). It was found that quinaldine red (QR) strongly bound to AGP and
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