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表单
powder
质量水平
组成
Dye content, 50%
技术
microbe id | staining: suitable
溶解性
H2O: 1 mg/mL
λmax
635 nm (2nd)
-410 nm
ε (消光系数)
≥50000 at 635-641 nm in H2O
≥5300 at 408-414 nm in H2O
≥7500 at 308-314 nm in H2O
应用
diagnostic assay manufacturing
hematology
histology
储存温度
room temp
SMILES字符串
[Na+].CCN(CC)c1ccc(cc1)\C(=C2/C=CC(\C=C2)=[N+](\CC)CC)c3ccc(cc3S([O-])(=O)=O)S([O-])(=O)=O
InChI
1S/C27H32N2O6S2.Na/c1-5-28(6-2)22-13-9-20(10-14-22)27(21-11-15-23(16-12-21)29(7-3)8-4)25-18-17-24(36(30,31)32)19-26(25)37(33,34)35;/h9-19H,5-8H2,1-4H3,(H-,30,31,32,33,34,35);/q;+1/p-1
InChI key
SJEYSFABYSGQBG-UHFFFAOYSA-M
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应用
使用了专利蓝 VF:
- 联合 99mTc 植酸钠检测早期宫颈癌患者前哨淋巴结 (SLN)。
- 检测热休克蛋白 (HSP) gp96 诱导的小鼠引流淋巴结 (LN)。
- 检测 Asn-Gly-Arg (NGR)-肿瘤坏死因子 (TNF) 对小鼠模型肿瘤灌注的影响。
生化/生理作用
专利蓝 VF 染料是紫色粉末。已用于化妆品着色。
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Blue dyes in medicine--a confusing terminology.
Kathrin Scherer et al.
Contact dermatitis, 54(4), 231-232 (2006-05-03)
Sentinel lymph node detection in early cervical cancer with combination 99mTc phytate and patent blue.
Niikura H
Gynecologic Oncology, 94(2), 528-532 (2004)
Synergistic antitumor activity of cisplatin, paclitaxel, and gemcitabine with tumor vasculature-targeted tumor necrosis factor-alpha.
Sacchi A
Clinical Cancer Research, 12(1), 175-182 (2006)
Cutting Edge: Heat Shock Protein gp96
Induces Maturation and Migration of
CD11c1 Cells In Vivo
Induces Maturation and Migration of
CD11c1 Cells In Vivo
Binder R J
Journal of Immunology, 165, 6029-6035 (2000)
S Zervoudis et al.
European journal of gynaecological oncology, 33(3), 304-305 (2012-08-10)
Sentinel lymph node (SLN) biopsy is a well established option for assessing axillary lymph node status in breast cancer. Several techniques have been applied so far (superficial or deeper ones). Based on anatomical features of the lymphatic drainage in the
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