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Merck
CN

19443

Andrograpanin

analytical standard

别名:

3,14-Dideoxyandrographolide, 3-[2-[(1R,4aS,5R,8aS)-Decahydro-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-2(5H)-furanone, ent-19-Hydroxy-8(17),13-labdadien-16,15-olide

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关于此项目

经验公式(希尔记法):
C20H30O3
化学文摘社编号:
分子量:
318.45
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
MDL number:
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InChI key

WKKBRRFSRMDTJB-JYBIWHBTSA-N

SMILES string

C[C@@]1(CO)CCC[C@@]2(C)[C@H](CCC3=CCOC3=O)C(=C)CC[C@H]12

InChI

1S/C20H30O3/c1-14-5-8-17-19(2,13-21)10-4-11-20(17,3)16(14)7-6-15-9-12-23-18(15)22/h9,16-17,21H,1,4-8,10-13H2,2-3H3/t16-,17-,19+,20+/m1/s1

grade

analytical standard

assay

≥95% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

Quality Level

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General description

Andrograpanin, diterpene lactone is a hydrolysate drug used as anti-inflammatory agent. It is a minor compound of Andrographis paniculata. It has the potential to modulate the chemokine pathway and is used in anti-infectious function. It may be used in treating infections, inflammation, cold, fever and diarrhea.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jun Liu et al.
International immunopharmacology, 8(7), 951-958 (2008-05-20)
Andrographis paniculata Nees is an official herbal medicine for treatment of infection and inflammation in China. Andrograpanin, the one of diterpene lactones in A. paniculata, is a hydrolysate from neoandrographolide in vivo and in vitro. The goal of the present
Li-Li Ji et al.
Journal of cellular biochemistry, 95(5), 970-978 (2005-06-07)
Andrographis paniculata is a traditional Chinese medicine (TCM) that has been effectively used for treatment of infection, inflammation, cold, fever, and diarrhea in China. However, mechanism of its therapeutic function is not well known. In the current study, we showed

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