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Merck
CN

18280

3-溴吡啶

purum, ≥97.0% (GC)

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经验公式(希尔记法):
C5H4BrN
化学文摘社编号:
分子量:
158.00
EC Number:
210-952-0
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
105880
MDL number:
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InChI key

NYPYPOZNGOXYSU-UHFFFAOYSA-N

InChI

1S/C5H4BrN/c6-5-2-1-3-7-4-5/h1-4H

SMILES string

Brc1cccnc1

grade

purum

assay

≥97.0% (GC)

bp

173 °C (lit.)

density

1.64 g/mL at 25 °C (lit.)

Application

3-Bromopyridine was used in the synthesis of cis-1-methyl-1,2,3,3a,4,8b-hexahydropyrrolo[3,2-f]pyrindine (a nicotine analog). It was also used in the preparation of 3-pyridylboronic acid.

pictograms

FlameExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

3 - Flammable liquids

wgk

WGK 3

flash_point_f

125.6 °F - closed cup

flash_point_c

52 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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Wenjie Li et al.
The Journal of organic chemistry, 67(15), 5394-5397 (2002-07-20)
3-Pyridylboronic acid was prepared in high yield and bulk quantity from 3-bromopyridine via a protocol of lithium-halogen exchange and "in situ quench". This technique was further studied and evaluated on other aryl halides in the preparation of arylboronic acids.
Hongbin Zhai et al.
Organic letters, 4(25), 4385-4386 (2002-12-06)
[reaction: see text] The title compound, 2, has been synthesized in 45% overall yield in six steps from 3-bromopyridine. The hexahydropyrrolo[3,2-f]pyrindine skeleton was constructed from key intermediate 5, via intramolecular azomethine ylide-alkene [3 + 2] cycloaddition. The present work constitutes

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