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Merck
CN

17970

Sigma-Aldrich

2,4′-二溴苯乙酮

puriss., ≥98.5% (HPLC)

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别名:
4′-溴苯甲酰甲基溴
线性分子式:
BrC6H4COCH2Br
CAS号:
分子量:
277.94
Beilstein:
607604
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:

等级

puriss.

检测方案

≥98.5% (HPLC)

形式

solid

mp

108-110 °C (lit.)
108-112 °C

SMILES字符串

BrCC(=O)c1ccc(Br)cc1

InChI

1S/C8H6Br2O/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4H,5H2

InChI key

FKJSFKCZZIXQIP-UHFFFAOYSA-N

基因信息

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一般描述

The effect of 2,4′-dibromoacetophenone on rat seminiferous tubules in vitro was studied.

其他说明

修饰蛋白质中组氨酸残基

替代产品

产品编号
说明
价格

象形图

Corrosion

警示用语:

Danger

危险声明

危险分类

Skin Corr. 1B

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

新产品

分析证书(COA)

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Taomin Huang et al.
Journal of pharmaceutical and biomedical analysis, 41(2), 644-648 (2006-01-18)
A simple, rapid and sensitive high-performance liquid chromatographic method for the simultaneous determination of captopril and hydrochlorothiazide in human plasma samples was developed. Captopril was derivatized with 2,4'-dibromoacetophenone (pBPB) to form a captopril-pBPB adduct. From acidified serum plasma samples, the
C H Farr et al.
Journal of reproduction and fertility, 58(1), 37-42 (1980-01-01)
The effects of prostaglandin (PG) F-2 alpha and E-2, cyclic GMP, testosterone and 2,4'-dibromoacetophenone (DBA) on rat seminiferous tubules in vitro were ascertained by measuring contractile frequency, size of contractions and tone (tubular diameter). PGF-2 alpha (10(-9)--10(-5) M) increased frequency
J Fohlman et al.
European journal of biochemistry, 94(2), 531-540 (1979-03-01)
Treatment of taipoxin with p-bromophenacyl bromide resulted in modification of single histidine residues in the alpha and beta subunits. The modification decreased the neurotoxicity (lethality) 350-fold, but the inhibitory action on high-affinity choline transport was reduced only threefold. The phospholipase
H M Verheij et al.
Biochemistry, 19(4), 743-750 (1980-02-19)
It is known that His-48 is part of the active center in pancreatic phospholipase. To further elucidate the role of histidine-48 in the active center of pancreatic phospholipase A2, we have modified the enzyme with a number of bromo ketones
Zhuo-Jia Chen et al.
Seizure, 21(2), 110-117 (2011-11-08)
Valproic acid (VPA) is a well-established anticonvulsant drug that has been increasingly used in the treatment of many forms of generalized epilepsy. Although there are many reports of adverse effects of VPA, studies focusing on the concentration-response relationships of VPA

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